Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 4724696..4725486 Replicon chromosome
Accession NZ_CP110782
Organism Pseudomonas putida DOT-T1E

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag OPZ46_RS21755 Protein ID WP_014859916.1
Coordinates 4725019..4725486 (+) Length 156 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID I7C311
Locus tag OPZ46_RS21750 Protein ID WP_014859917.1
Coordinates 4724696..4725022 (+) Length 109 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OPZ46_RS21730 (OPZ46_21730) 4720211..4721272 - 1062 WP_014859921.1 HlyD family secretion protein -
OPZ46_RS21735 (OPZ46_21735) 4721301..4722842 - 1542 WP_014859920.1 MFS transporter -
OPZ46_RS21740 (OPZ46_21740) 4722978..4723883 - 906 WP_014859919.1 LysR family transcriptional regulator -
OPZ46_RS21745 (OPZ46_21745) 4724157..4724603 + 447 WP_014859918.1 universal stress protein -
OPZ46_RS21750 (OPZ46_21750) 4724696..4725022 + 327 WP_014859917.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
OPZ46_RS21755 (OPZ46_21755) 4725019..4725486 + 468 WP_014859916.1 type II toxin-antitoxin system YhaV family toxin Toxin
OPZ46_RS21760 (OPZ46_21760) 4725559..4726419 - 861 WP_014859915.1 HlyD family secretion protein -
OPZ46_RS21765 (OPZ46_21765) 4726430..4726630 - 201 WP_014859914.1 DUF1656 domain-containing protein -
OPZ46_RS21770 (OPZ46_21770) 4726620..4728797 - 2178 WP_003251716.1 FUSC family protein -
OPZ46_RS21775 (OPZ46_21775) 4728794..4730323 - 1530 WP_014859913.1 efflux transporter outer membrane subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(17-152)

Antitoxin

PrlF antitoxin

(8-106)


Sequences

Toxin        


Download         Length: 156 a.a.        Molecular weight: 17998.38 Da        Isoelectric Point: 9.7964

>T264218 WP_014859916.1 NZ_CP110782:4725019-4725486 [Pseudomonas putida DOT-T1E]
MSDASRKPLVIHGWTVIAHPLFLAKLDALSAQVEAQRDKDPTGYTKRNTFKRLAAIRRLAFDVIPQDPTKPEYRQGATLG
GDHKHWFRAKFFQQYRLFFRYHTPSRIIVLAWVNDESSKRAYESNDDAYKVFQKMLHSGHPPDDWDQLLQEAAAD

Download         Length: 468 bp

Antitoxin


Download         Length: 109 a.a.        Molecular weight: 11919.40 Da        Isoelectric Point: 4.3722

>AT264218 WP_014859917.1 NZ_CP110782:4724696-4725022 [Pseudomonas putida DOT-T1E]
MAATFDVESTLTDRYQTTVPETVRRALGLKKRDKIHYSIRPDGGVILTRAEATEDDPVLGKFLDFLAHDIATNPQRLQVV
DAGLIARLDKLVGDAEVDLDQPLSADDE

Download         Length: 327 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB I7C311

References