Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-PumB/upstrm_HI1419-dnstrm_HI1420
Location 259916..260502 Replicon chromosome
Accession NZ_CP110782
Organism Pseudomonas putida DOT-T1E

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OPZ46_RS01185 Protein ID WP_128573832.1
Coordinates 259916..260161 (+) Length 82 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag OPZ46_RS01190 Protein ID WP_014861463.1
Coordinates 260206..260502 (+) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OPZ46_RS01160 (OPZ46_01160) 255517..256371 + 855 WP_014861459.1 putative selenate ABC transporter substrate-binding protein -
OPZ46_RS01165 (OPZ46_01165) 256368..257177 + 810 WP_014861460.1 phosphonate ABC transporter ATP-binding protein -
OPZ46_RS01170 (OPZ46_01170) 257171..257998 + 828 WP_004576350.1 ABC transporter permease subunit -
OPZ46_RS01175 (OPZ46_01175) 257995..258762 + 768 WP_014861461.1 phosphonate ABC transporter, permease protein PhnE -
OPZ46_RS01180 (OPZ46_01180) 258799..259692 - 894 WP_014861462.1 bestrophin family ion channel -
OPZ46_RS01185 (OPZ46_01185) 259916..260161 + 246 WP_128573832.1 addiction module antitoxin RelB Toxin
OPZ46_RS01190 (OPZ46_01190) 260206..260502 + 297 WP_014861463.1 putative addiction module antidote protein Antitoxin
OPZ46_RS01195 (OPZ46_01195) 260513..260992 - 480 WP_014861464.1 GNAT family N-acetyltransferase -
OPZ46_RS01200 (OPZ46_01200) 261101..261748 - 648 WP_121782881.1 serine protease -
OPZ46_RS01205 (OPZ46_01205) 262092..262514 + 423 WP_012051239.1 VOC family protein -
OPZ46_RS01210 (OPZ46_01210) 262524..262640 - 117 Protein_228 effector protein -
OPZ46_RS01215 (OPZ46_01215) 263076..264491 + 1416 WP_108078299.1 FAD-binding oxidoreductase -
OPZ46_RS01220 (OPZ46_01220) 264571..265068 + 498 WP_014589747.1 RidA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(2-81)

Antitoxin

Uncharacterized protein HI1420

(5-91)


Sequences

Toxin        


Download         Length: 82 a.a.        Molecular weight: 8927.34 Da        Isoelectric Point: 10.6759

>T264216 WP_128573832.1 NZ_CP110782:259916-260161 [Pseudomonas putida DOT-T1E]
MFLVEQTESFAAWLSSLRDLRARLAIGRRLERAAAGNLGDFKWLGGGIGELRIDVAAGYRVYFTQKGQRLVLLLVGGDKS
T

Download         Length: 246 bp

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 10706.42 Da        Isoelectric Point: 6.7249

>AT264216 WP_014861463.1 NZ_CP110782:260206-260502 [Pseudomonas putida DOT-T1E]
MSEKLIPFDMAALLSSDEAISEYLSQVLSNGDTEEIIRALGHIARARGMTHIAMESGLGRESLYKALSPGAKPRFDTVLR
VIRALGVDLLVQPHAMTR

Download         Length: 297 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References