Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) pemIK/PRK09812-ChpS
Location 1466440..1467030 Replicon chromosome
Accession NZ_CP110473
Organism Pantoea anthophila strain CL1

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag OJ965_RS09310 Protein ID WP_265138960.1
Coordinates 1466698..1467030 (+) Length 111 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag OJ965_RS09305 Protein ID WP_046102165.1
Coordinates 1466440..1466697 (+) Length 86 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OJ965_RS09290 (OJ965_09290) 1461468..1462241 - 774 WP_154927662.1 PhnD/SsuA/transferrin family substrate-binding protein -
OJ965_RS09295 (OJ965_09295) 1462461..1463483 + 1023 WP_046102167.1 LLM class flavin-dependent oxidoreductase -
OJ965_RS09300 (OJ965_09300) 1463898..1466129 + 2232 WP_009089362.1 catalase/peroxidase HPI -
OJ965_RS09305 (OJ965_09305) 1466440..1466697 + 258 WP_046102165.1 antitoxin Antitoxin
OJ965_RS09310 (OJ965_09310) 1466698..1467030 + 333 WP_265138960.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
OJ965_RS09320 (OJ965_09320) 1467505..1468626 + 1122 WP_140028954.1 Gfo/Idh/MocA family oxidoreductase -
OJ965_RS09325 (OJ965_09325) 1468695..1469525 - 831 WP_265138961.1 glycosyltransferase family 8 protein -
OJ965_RS09330 (OJ965_09330) 1469534..1470916 - 1383 WP_140925557.1 D-arabinono-1,4-lactone oxidase -
OJ965_RS09335 (OJ965_09335) 1471000..1471632 - 633 WP_046102260.1 TetR family transcriptional regulator -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-109)

Antitoxin

(5-84)


Sequences


Toxin        


Download         Length: 111 a.a.        Molecular weight: 11993.82 Da        Isoelectric Point: 8.5695

>T263834 WP_265138960.1 NZ_CP110473:1466698-1467030 [Pantoea anthophila]
MERGEIWLVTLDPTAGHEQSGRRPVLIVSPASFNAFTRLPIVVPVTRGGNFARAAGFAVSLDGAGCRTKGVVRCDQPRTL
DMEAREGRRLERLPDAIVNEVLARLEAILN

Download         Length: 333 bp


Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9337.84 Da        Isoelectric Point: 6.9773

>AT263834 WP_046102165.1 NZ_CP110473:1466440-1466697 [Pantoea anthophila]
MFITRLKKVGGSVMLAVPPAVLKTLSLSANSEVGMTIDNGYLIVKPRTRPRYSLEELLAQCDPHAEISKEDRDWIDAPAA
GKENL

Download         Length: 258 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References