Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 477640..478117 Replicon chromosome
Accession NZ_CP110418
Organism Veillonella rogosae strain KCOM 3468

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag OKW85_RS02035 Protein ID WP_265138552.1
Coordinates 477851..478117 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag OKW85_RS02030 Protein ID WP_265138551.1
Coordinates 477640..477861 (+) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OKW85_RS02010 (OKW85_02010) 473878..474768 + 891 WP_265138547.1 phosphate ABC transporter substrate-binding protein -
OKW85_RS02015 (OKW85_02015) 474826..475707 + 882 WP_265138548.1 phosphate ABC transporter permease subunit PstC -
OKW85_RS02020 (OKW85_02020) 475694..476512 + 819 WP_265138549.1 ABC transporter permease subunit -
OKW85_RS02025 (OKW85_02025) 476512..477255 + 744 WP_265138550.1 ATP-binding cassette domain-containing protein -
OKW85_RS02030 (OKW85_02030) 477640..477861 + 222 WP_265138551.1 DUF6290 family protein Antitoxin
OKW85_RS02035 (OKW85_02035) 477851..478117 + 267 WP_265138552.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OKW85_RS02040 (OKW85_02040) 478128..478340 + 213 WP_265138553.1 hypothetical protein -
OKW85_RS02045 (OKW85_02045) 478507..479298 - 792 WP_265138554.1 carbon-nitrogen family hydrolase -
OKW85_RS02050 (OKW85_02050) 479539..480342 + 804 WP_009351987.1 polysaccharide deacetylase family protein -
OKW85_RS02055 (OKW85_02055) 480354..481292 + 939 WP_009351887.1 phosphodiester glycosidase family protein -
OKW85_RS02060 (OKW85_02060) 481301..482248 + 948 WP_265138555.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-87)

Antitoxin

Protein of unknown function DUF6290

(1-69)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10601.31 Da        Isoelectric Point: 10.4134

>T263823 WP_265138552.1 NZ_CP110418:477851-478117 [Veillonella rogosae]
MAYKLEFSKRFDKQFSKLDKSTQRYLFNWLIKNVDNVDNPRYLGKSLMGNKTGLWRYRIGNYRVIADINDHRCIILALEV
GHRKDIYK

Download         Length: 267 bp

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8499.71 Da        Isoelectric Point: 4.3700

>AT263823 WP_265138551.1 NZ_CP110418:477640-477861 [Veillonella rogosae]
MANISVRLNKQEEELFKTYAEFMDETLSTLFKKALLEKIEDEFDLKVGQKALAEYEQDPVTYSVAEMRAKYGL

Download         Length: 222 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References