Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 5671876..5672471 Replicon chromosome
Accession NZ_CP110346
Organism Pseudomonas aeruginosa strain PALA35

Toxin (Protein)


Gene name higB Uniprot ID V6ALY3
Locus tag PALA35_RS26380 Protein ID WP_003113526.1
Coordinates 5672193..5672471 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag PALA35_RS26375 Protein ID WP_031638452.1
Coordinates 5671876..5672181 (-) Length 102 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
- 5671876..5672181 - 306 - - Antitoxin
- 5672193..5672471 - 279 - - Toxin

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(5-92)

Antitoxin

(6-82)


Sequences


Toxin        


Download         Length: 93 a.a.        Molecular weight: 10646.19 Da        Isoelectric Point: 7.8937

>T263651 WP_003113526.1 NZ_CP110346:c5672471-5672193 [Pseudomonas aeruginosa]
MILTFRCDETRQLFETGLSRRWGAILTVATRKLAMLHAATELRDLRSPPGNRLEPLQGKRAGQHSIRINDQWRVCFVWTD
AGPEEVEIVDYH

Download         Length: 279 bp


Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11156.70 Da        Isoelectric Point: 4.7860

>AT263651 WP_031638452.1 NZ_CP110346:c5672181-5671876 [Pseudomonas aeruginosa]
MATNGMRPIHPGEILRDEFLMELGISPAALARALKVSAPTVNDIVREQRGISADMAIRLGRYFDTSAQFWMNLQSEYSLA
TAYAANGEQIEHEIEPLLAHG

Download         Length: 306 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB V6ALY3


Antitoxin

Source ID Structure

References