Detailed information of TA system TA026351

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): bsrG-as-bsrG/-
• Location: 1185509..1185759
• Replicon: chromosome
• Accession: NC_017188
• Organism: Bacillus amyloliquefaciens TA208

Toxin (Protein)

• Gene name: bsrG
• Uniprot ID: L8EAY0
• Locus tag: BAMTA208_RS20610
• Protein ID: WP_009967548.1
• Coordinates: 1185643..1185759 (-)
• Length: 39 a.a.

Antitoxin (RNA)

Gene name	as-bsrG
Locus tag	-
Coordinates	1185509..1185648 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BAMTA208_RS05915	1181223..1181657	+	435	WP_076982859.1	SMI1/KNR4 family protein	-
BAMTA208_RS05920	1181701..1182471	-	771	WP_014470068.1	hypothetical protein	-
BAMTA208_RS05925	1182978..1184864	+	1887	WP_014470069.1	HNH endonuclease	-
BAMTA208_RS05930	1184877..1185335	+	459	WP_014470070.1	SMI1/KNR4 family protein	-
-	1185509..1185648	+	140	NuclAT_0	-	Antitoxin
-	1185509..1185648	+	140	NuclAT_0	-	Antitoxin
-	1185509..1185648	+	140	NuclAT_0	-	Antitoxin
-	1185509..1185648	+	140	NuclAT_0	-	Antitoxin
BAMTA208_RS20610	1185643..1185759	-	117	WP_009967548.1	type I toxin-antitoxin system toxin BsrG	Toxin
BAMTA208_RS05935	1185988..1186191	+	204	WP_014470071.1	hypothetical protein	-
BAMTA208_RS05940	1186426..1187090	+	665	Protein_1156	sporulation protein YunB	-
BAMTA208_RS05945	1187309..1187641	+	333	WP_014470072.1	YolD-like family protein	-
BAMTA208_RS05950	1187634..1188884	+	1251	WP_014470073.1	UV-damage repair protein uvrX	-
BAMTA208_RS05955	1189048..1190210	-	1163	Protein_1159	tetratricopeptide repeat protein	-
BAMTA208_RS20530	1190362..1190622	-	261	WP_014472510.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	1177769..1325962	148193

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Small toxic protein BsrE-like (1-38)

Sequences

Toxin

Protein

• Length: 39 a.a.
• Molecular weight: 4336.39 Da
• Isoelectric Point: 10.1022

>T26351 WP_009967548.1 NC_017188:c1185759-1185643 [Bacillus amyloliquefaciens TA208]
MTVYESLMIMINFGGLILNTVLLIFNIMMIVTSSQKKK

Nucleotide

• Length: 117 bp

>T26351 NC_017188:c1185759-1185643 [Bacillus amyloliquefaciens TA208]
ATGACTGTTTACGAATCATTAATGATAATGATCAATTTTGGCGGATTGATATTAAATACCGTCTTGTTGATCTTCAATAT
AATGATGATTGTAACGTCAAGCCAAAAGAAAAAATAG

Antitoxin

Nucleotide

• Length: 140 bp

>AT26351 NC_017188:1185509-1185648 [Bacillus amyloliquefaciens TA208]
AAATGCATAAAATAAAAAGACCAGGGTGTTGGTAGCACCCCGGCTCTGTACAAAAAGCTGCCCATCAAAGGGCTTGCTCG
ATGTTGAATCTGCGTAGACCTAACCCTTTAAGGTTCCTAAGCTCAAGGGAAGGTCTATTT

Structures

Toxin

• AlphaFold DB: A0A7Z7EVU9

Antitoxin