Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) hok-sok/-
Location 2239781..2240039 Replicon chromosome
Accession NZ_CP110260
Organism Escherichia albertii strain KBSW16i

Toxin (Protein)


Gene name hokC Uniprot ID S1NX00
Locus tag N6N74_RS11205 Protein ID WP_000809168.1
Coordinates 2239887..2240039 (+) Length 51 a.a.

Antitoxin (RNA)


Gene name sokC
Locus tag -
Coordinates 2239781..2239838 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N6N74_RS11190 2235588..2236835 - 1248 WP_044708455.1 hypothetical protein -
N6N74_RS11195 2236989..2238482 - 1494 WP_059216552.1 sulfatase-like hydrolase/transferase -
N6N74_RS11200 2238503..2239264 - 762 WP_059216553.1 outer membrane protein OmpK -
- 2239781..2239838 - 58 - - Antitoxin
N6N74_RS11205 2239887..2240039 + 153 WP_000809168.1 type I toxin-antitoxin system toxin MokC Toxin
N6N74_RS11210 2240143..2241273 - 1131 WP_001118445.1 molecular chaperone DnaJ -
N6N74_RS11215 2241362..2243278 - 1917 WP_000516135.1 molecular chaperone DnaK -
N6N74_RS11220 2243653..2244057 + 405 WP_000833521.1 DUF2541 family protein -
N6N74_RS11225 2244084..2244797 + 714 WP_001102345.1 acidic protein MsyB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Hok/gef cell toxic protein

(6-47)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5501.57 Da        Isoelectric Point: 7.1312

>T263508 WP_000809168.1 NZ_CP110260:2239887-2240039 [Escherichia albertii]
MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYESE

Download         Length: 153 bp

Antitoxin


Download         Length: 58 bp

>AT263508 NZ_CP110260:c2239838-2239781 [Escherichia albertii]
GTTCTGCATATAGGGGGCCTCGGGTTGATGGTAAAATATCACTCGGGGCTTTTCTCTA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB S1NX00

Antitoxin

Download structure file

References