263177

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rnlAB/RnlA-RnlB
Location 5451014..5452435 Replicon chromosome
Accession NZ_CP110128
Organism Pseudomonas sp. WJP1

Toxin (Protein)


Gene name rnlA Uniprot ID -
Locus tag OH720_RS24385 Protein ID WP_272603220.1
Coordinates 5451362..5452435 (-) Length 358 a.a.

Antitoxin (Protein)


Gene name rnlB Uniprot ID -
Locus tag OH720_RS24380 Protein ID WP_272603219.1
Coordinates 5451014..5451307 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OH720_RS24370 (OH720_24375) 5447704..5449479 + 1776 WP_272603217.1 bifunctional diguanylate cyclase/phosphodiesterase -
OH720_RS24375 (OH720_24380) 5449984..5450724 + 741 WP_272603218.1 toll/interleukin-1 receptor domain-containing protein -
OH720_RS24380 (OH720_24385) 5451014..5451307 - 294 WP_272603219.1 type II toxin-antitoxin system RnlB family antitoxin Antitoxin
OH720_RS24385 (OH720_24390) 5451362..5452435 - 1074 WP_272603220.1 type II toxin-antitoxin system RnlA family toxin Toxin
OH720_RS24390 (OH720_24395) 5452721..5453062 - 342 WP_272603221.1 hypothetical protein -
OH720_RS24395 (OH720_24400) 5453309..5453716 - 408 WP_272603222.1 sel1 repeat family protein -
OH720_RS24400 (OH720_24405) 5453717..5454088 - 372 WP_008060892.1 hypothetical protein -
OH720_RS24405 (OH720_24410) 5454085..5454426 - 342 WP_272603223.1 helix-turn-helix transcriptional regulator -
OH720_RS24410 (OH720_24415) 5454541..5454996 - 456 WP_272603224.1 YkvA family protein -
OH720_RS24415 (OH720_24420) 5455292..5456005 - 714 WP_008060887.1 FKBP-type peptidyl-prolyl cis-trans isomerase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Bacterial toxin, RNase RnlA/LsoA, N-terminal

(6-87)

Antitoxin

Antitoxin RnlB/LsoB

(2-96)


Sequences

Toxin        


Download         Length: 358 a.a.        Molecular weight: 39957.51 Da        Isoelectric Point: 6.1138

>T263177 WP_272603220.1 NZ_CP110128:c5452435-5451362 [Pseudomonas sp. WJP1]
VTDRTYKDINLNRAIIEETIVRFVDVNGIKLRGIGEKPGSPGIRVGIGSAGIEDATVEIFFNNTGTSTLHYKLGKNQELG
QKLADALYETIHPDDFVTINLGIKGIDLSDAQALIKELTESVNADIEVASYTKGERRNIWKLKSKKNSDELTVTQHETTN
KLQLQGRPLSCYRELSYLLTEILEVNALECILFKKEENRSEFVCTEVAESVLKDRFGTCFENLPVATRKLLLASLCVRLA
SPALPDYCMLVYPELRSLEGAIKHKLSEKNLSNQEDSFGGFFTKTSGQFNLKQQYQADVNDAKLQSVLGDAYTFFNKHRH
GLFHMEEMPSASRMISSITQAVALCDEAYAHLKTLYG

Download         Length: 1074 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 11079.39 Da        Isoelectric Point: 4.3988

>AT263177 WP_272603219.1 NZ_CP110128:c5451307-5451014 [Pseudomonas sp. WJP1]
MTVVTATSYENPLSSLSAIASMMRNTSHTGKEIVLFDLLCSNGEEWNRFAFINYNGTDFERSTFSIVSRCDIPSDLIETQ
TRFFEVHPEYLRDSVLN

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References