26184

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vapBC/VapC-MazE
Location 474055..474534 Replicon chromosome
Accession NC_017039
Organism Synechocystis sp. PCC 6803 substr. PCC-P

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag SYNPCCP_RS02260 Protein ID WP_010871640.1
Coordinates 474055..474306 (-) Length 84 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag SYNPCCP_RS02265 Protein ID WP_010871641.1
Coordinates 474307..474534 (-) Length 76 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SYNPCCP_RS02240 469103..469648 - 546 WP_010871636.1 alpha/beta hydrolase -
SYNPCCP_RS02245 469694..471016 + 1323 WP_010871637.1 hypothetical protein -
SYNPCCP_RS02250 471182..473032 + 1851 WP_010871638.1 ATP-dependent zinc metalloprotease FtsH3 -
SYNPCCP_RS02255 473190..473777 + 588 Protein_443 IS5 family transposase -
SYNPCCP_RS02260 474055..474306 - 252 WP_010871640.1 type II toxin-antitoxin system VapC family toxin Toxin
SYNPCCP_RS02265 474307..474534 - 228 WP_010871641.1 virulence factor Antitoxin
SYNPCCP_RS02270 474613..474894 - 282 WP_020861443.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family -
SYNPCCP_RS02275 474891..475109 - 219 WP_010871642.1 hypothetical protein -
SYNPCCP_RS02280 475212..475547 - 336 WP_010871643.1 DUF86 domain-containing protein -
SYNPCCP_RS02285 475537..475845 - 309 WP_010871644.1 nucleotidyltransferase family protein -
SYNPCCP_RS02290 475975..477501 - 1527 WP_010871645.1 RNA-directed DNA polymerase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
flank IS/Tn - - 473516..473764 248


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(3-80)

Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 84 a.a.        Molecular weight: 9540.13 Da        Isoelectric Point: 7.9952

>T26184 WP_010871640.1 NC_017039:c474306-474055 [Synechocystis sp. PCC 6803 substr. PCC-P]
MKYLLDTNICIYLIKKKPFKVLAKFQTLEISDIGISSITVAELEYGVSKSQQQSKNRDALMQFLMPLEIVEFNSGSGDRL
WQH

Download         Length: 252 bp

>T26184 NC_017039:c474306-474055 [Synechocystis sp. PCC 6803 substr. PCC-P]
ATGAAGTATTTACTAGATACGAATATTTGCATTTATCTCATTAAGAAGAAACCGTTTAAAGTCTTGGCAAAATTTCAAAC
CCTGGAGATATCAGACATTGGTATTTCATCCATTACCGTGGCGGAATTAGAATATGGTGTCAGTAAAAGTCAACAACAAT
CGAAAAATCGTGATGCCTTAATGCAATTCTTGATGCCGCTAGAAATCGTGGAATTTAATTCAGGAAGCGGCGATCGCCTA
TGGCAACATTAG

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8538.69 Da        Isoelectric Point: 4.2840

>AT26184 WP_010871641.1 NC_017039:c474534-474307 [Synechocystis sp. PCC 6803 substr. PCC-P]
MNTAQISTDGTHQIVILPENFTIAGSEVYIKKIGSTIILIAKNNPWQSLIESLDQFSDDFMKTREQPPLDIREEF

Download         Length: 228 bp

>AT26184 NC_017039:c474534-474307 [Synechocystis sp. PCC 6803 substr. PCC-P]
ATGAACACAGCTCAAATTAGCACCGATGGCACCCATCAAATCGTTATTTTACCAGAAAACTTTACGATAGCCGGAAGCGA
AGTTTACATTAAAAAAATTGGAAGTACAATTATTTTGATTGCTAAAAATAACCCTTGGCAATCCTTAATTGAAAGCTTAG
ATCAATTTTCAGATGATTTTATGAAAACTAGGGAACAGCCTCCCTTAGATATACGAGAAGAGTTCTAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References