Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2075116..2075261 Replicon chromosome
Accession NZ_CP107463
Organism Klebsiella pneumoniae strain CRKP_12

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2075152..2075254 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2075116..2075261 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OH534_RS10255 2070246..2072306 + 2061 WP_004151449.1 oligopeptidase B -
OH534_RS10260 2072310..2072969 - 660 WP_002911407.1 exodeoxyribonuclease X -
OH534_RS10265 2073048..2073278 - 231 WP_002911406.1 DNA polymerase III subunit theta -
OH534_RS10270 2073391..2073765 + 375 WP_004151448.1 CopC domain-containing protein YobA -
OH534_RS10275 2073769..2074638 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
OH534_RS10280 2074655..2074993 + 339 WP_002911404.1 YebY family protein -
- 2075116..2075261 - 146 - - Antitoxin
- 2075152..2075254 + 103 - - Toxin
OH534_RS10285 2075629..2075772 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
OH534_RS10290 2075877..2076845 - 969 WP_004151446.1 VirK/YbjX family protein -
OH534_RS10295 2077002..2077655 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
OH534_RS10300 2077652..2077843 - 192 WP_002911395.1 YebW family protein -
OH534_RS10305 2077941..2078180 - 240 WP_002911393.1 YebV family protein -
OH534_RS10310 2078296..2079729 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T261410 NZ_CP107463:2075152-2075254 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT261410 NZ_CP107463:c2075261-2075116 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References