Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 760516..760661 Replicon chromosome
Accession NZ_CP107390
Organism Klebsiella pneumoniae strain CRKP_28

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 760523..760625 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 760516..760661 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OH501_RS03870 756048..757481 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
OH501_RS03875 757597..757836 + 240 WP_002911393.1 YebV family protein -
OH501_RS03880 757934..758125 + 192 WP_002911395.1 YebW family protein -
OH501_RS03885 758122..758775 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
OH501_RS03890 758932..759900 + 969 WP_004151446.1 VirK/YbjX family protein -
OH501_RS03895 760005..760148 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 760516..760661 + 146 - - Antitoxin
- 760523..760625 - 103 - - Toxin
OH501_RS03900 760784..761122 - 339 WP_002911404.1 YebY family protein -
OH501_RS03905 761139..762008 - 870 WP_062955019.1 copper homeostasis membrane protein CopD -
OH501_RS03910 762012..762386 - 375 WP_004151448.1 CopC domain-containing protein YobA -
OH501_RS03915 762499..762729 + 231 WP_002911406.1 DNA polymerase III subunit theta -
OH501_RS03920 762808..763467 + 660 WP_002911407.1 exodeoxyribonuclease X -
OH501_RS03925 763471..765531 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T261040 NZ_CP107390:c760625-760523 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT261040 NZ_CP107390:760516-760661 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References