Detailed information of TA system TA026092

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): ygfYX/Cpta(toxin)
• Location: 1509513..1510182
• Replicon: chromosome
• Accession: NC_016901
• Organism: Shewanella baltica OS678

Toxin (Protein)

• Gene name: ygfX
• Uniprot ID: A9L5M8
• Locus tag: SBAL678_RS29840
• Protein ID: WP_012088602.1
• Coordinates: 1509742..1510182 (+)
• Length: 147 a.a.

Antitoxin (Protein)

• Gene name: ygfY
• Uniprot ID: -
• Locus tag: SBAL678_RS29835
• Protein ID: WP_006080770.1
• Coordinates: 1509513..1509761 (+)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SBAL678_RS29810	1505170..1505979	+	810	WP_006085061.1	prolipoprotein diacylglyceryl transferase	-
SBAL678_RS29815	1505976..1506770	+	795	WP_006085062.1	thymidylate synthase	-
SBAL678_RS29820	1506888..1508057	+	1170	WP_006085063.1	Na+/H+ antiporter NhaA	-
SBAL678_RS29825	1508060..1508446	+	387	WP_006080768.1	hypothetical protein	-
SBAL678_RS29830	1508519..1509427	+	909	WP_006085064.1	transcriptional activator NhaR	-
SBAL678_RS29835	1509513..1509761	+	249	WP_006080770.1	succinate dehydrogenase assembly factor 2	Antitoxin
SBAL678_RS29840	1509742..1510182	+	441	WP_012088602.1	hypothetical protein	Toxin
SBAL678_RS29845	1510242..1511855	-	1614	WP_012196790.1	L-aspartate oxidase	-
SBAL678_RS29850	1512045..1512623	+	579	WP_006080773.1	RNA polymerase sigma factor RpoE	-
SBAL678_RS29855	1512665..1513291	+	627	WP_006080774.1	anti-sigma factor	-
SBAL678_RS29860	1513304..1514236	+	933	WP_006080775.1	MucB/RseB C-terminal domain-containing protein	-
SBAL678_RS29865	1514247..1514720	+	474	WP_006080776.1	SoxR reducing system RseC family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Inner membrane protein YgfX (6-135)

Antitoxin

• Flavinator of succinate dehydrogenase (7-77)

Sequences

Toxin

Protein

• Length: 147 a.a.
• Molecular weight: 17252.42 Da
• Isoelectric Point: 8.3668

>T26092 WP_012088602.1 NC_016901:1509742-1510182 [Shewanella baltica OS678]
VEDRHHSFSVKASFDQRLSLVVFICVCASSFLLWPQSDNLALSLLKYLFILLVCIFLLSQLWRLQHWRLDFVLSDKGVGR
LSTGEHFQVLKRTWVTPFVCLMYIEVDTQLRLLMVWADMLDDTDYRHLCRLLLRAKIKQTKPHTEI

Nucleotide

• Length: 441 bp

>T26092 NC_016901:1509742-1510182 [Shewanella baltica OS678]
GTGGAAGACCGGCACCATAGTTTCAGCGTAAAAGCCTCCTTCGACCAACGACTCTCGTTGGTCGTTTTTATTTGTGTCTG
TGCTAGCTCATTTCTGCTCTGGCCTCAAAGCGACAATCTCGCCTTATCCCTGCTTAAATATCTGTTTATCCTGCTAGTTT
GTATTTTCTTGCTATCACAGTTGTGGCGACTGCAGCATTGGCGTTTAGATTTTGTGCTTAGTGATAAAGGCGTGGGACGT
TTGTCAACGGGTGAGCACTTTCAGGTATTAAAGCGAACTTGGGTGACGCCCTTTGTTTGCTTGATGTACATCGAAGTGGA
TACTCAGTTACGGCTCTTGATGGTTTGGGCGGATATGTTAGACGATACTGACTATCGGCATTTATGTCGGCTGTTGCTGC
GGGCTAAAATAAAACAGACTAAACCTCATACCGAGATTTAG

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 9723.36 Da
• Isoelectric Point: 4.4929

>AT26092 WP_006080770.1 NC_016901:1509513-1509761 [Shewanella baltica OS678]
MELMNIARVRWACRRGMLELDVLFQPFVENFYQEMSDEDKTVFIRLLECEDPELFAWFMGHEVCPDAELARMVVKVRGRP
AP

Nucleotide

• Length: 249 bp

>AT26092 NC_016901:1509513-1509761 [Shewanella baltica OS678]
TTGGAATTAATGAACATCGCAAGGGTTCGCTGGGCATGTCGCCGCGGGATGCTAGAATTAGACGTTTTGTTTCAACCTTT
TGTTGAAAATTTCTATCAAGAAATGTCCGATGAAGATAAAACTGTGTTTATCCGTTTGTTGGAATGTGAAGATCCCGAAT
TGTTTGCATGGTTTATGGGCCATGAAGTGTGCCCTGATGCTGAGCTCGCGCGTATGGTAGTGAAAGTCCGTGGAAGACCG
GCACCATAG

Structures

Toxin

• AlphaFold DB: A9L5M8