Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 697843..697988 Replicon chromosome
Accession NZ_CP107363
Organism Klebsiella pneumoniae strain CRKP_33

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 697850..697952 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 697843..697988 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OH511_RS03495 693375..694808 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
OH511_RS03500 694924..695163 + 240 WP_002911393.1 YebV family protein -
OH511_RS03505 695261..695452 + 192 WP_002911395.1 YebW family protein -
OH511_RS03510 695449..696102 - 654 WP_004180432.1 protein-serine/threonine phosphatase -
OH511_RS03515 696259..697227 + 969 WP_004151446.1 VirK/YbjX family protein -
OH511_RS03520 697332..697475 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 697843..697988 + 146 - - Antitoxin
- 697850..697952 - 103 - - Toxin
OH511_RS03525 698111..698449 - 339 WP_002911404.1 YebY family protein -
OH511_RS03530 698466..699335 - 870 WP_062955019.1 copper homeostasis membrane protein CopD -
OH511_RS03535 699339..699713 - 375 WP_004151448.1 CopC domain-containing protein YobA -
OH511_RS03540 699826..700056 + 231 WP_002911406.1 DNA polymerase III subunit theta -
OH511_RS03545 700135..700794 + 660 WP_002911407.1 exodeoxyribonuclease X -
OH511_RS03550 700798..702858 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T260919 NZ_CP107363:c697952-697850 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT260919 NZ_CP107363:697843-697988 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References