Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2012536..2012681 Replicon chromosome
Accession NZ_CP107291
Organism Klebsiella pneumoniae strain CRKP_45

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2012572..2012674 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2012536..2012681 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OH513_RS09875 2007666..2009726 + 2061 WP_004151449.1 oligopeptidase B -
OH513_RS09880 2009730..2010389 - 660 WP_002911407.1 exodeoxyribonuclease X -
OH513_RS09885 2010468..2010698 - 231 WP_002911406.1 DNA polymerase III subunit theta -
OH513_RS09890 2010811..2011185 + 375 WP_004151448.1 CopC domain-containing protein YobA -
OH513_RS09895 2011189..2012058 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
OH513_RS09900 2012075..2012413 + 339 WP_002911404.1 YebY family protein -
- 2012536..2012681 - 146 - - Antitoxin
- 2012572..2012674 + 103 - - Toxin
OH513_RS09905 2013049..2013192 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
OH513_RS09910 2013297..2014265 - 969 WP_004151446.1 VirK/YbjX family protein -
OH513_RS09915 2014422..2015075 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
OH513_RS09920 2015072..2015263 - 192 WP_002911395.1 YebW family protein -
OH513_RS09925 2015361..2015600 - 240 WP_002911393.1 YebV family protein -
OH513_RS09930 2015716..2017149 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T260632 NZ_CP107291:2012572-2012674 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT260632 NZ_CP107291:c2012681-2012536 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References