Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4780558..4780703 Replicon chromosome
Accession NZ_CP107043
Organism Klebsiella pneumoniae strain KPTA-2108

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4780594..4780696 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4780558..4780703 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OEC00_RS23290 4775688..4777748 + 2061 WP_004151449.1 oligopeptidase B -
OEC00_RS23295 4777752..4778411 - 660 WP_021440386.1 exodeoxyribonuclease X -
OEC00_RS23300 4778490..4778720 - 231 WP_002911406.1 DNA polymerase III subunit theta -
OEC00_RS23305 4778833..4779207 + 375 WP_004151448.1 CopC domain-containing protein YobA -
OEC00_RS23310 4779211..4780080 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
OEC00_RS23315 4780097..4780435 + 339 WP_002911404.1 YebY family protein -
- 4780558..4780703 - 146 - - Antitoxin
- 4780594..4780696 + 103 - - Toxin
OEC00_RS23320 4781072..4781215 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
OEC00_RS23325 4781320..4782288 - 969 WP_004151446.1 VirK/YbjX family protein -
OEC00_RS23330 4782445..4783098 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
OEC00_RS23335 4783095..4783286 - 192 WP_002911395.1 YebW family protein -
OEC00_RS23340 4783384..4783623 - 240 WP_002911393.1 YebV family protein -
OEC00_RS23345 4783739..4785172 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T260488 NZ_CP107043:4780594-4780696 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT260488 NZ_CP107043:c4780703-4780558 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References