Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 2709606..2710131 Replicon chromosome
Accession NZ_CP107020
Organism Brachybacterium huguangmaarense strain BRM-3

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag BRM3_RS12470 Protein ID WP_263595464.1
Coordinates 2709606..2709863 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag BRM3_RS12475 Protein ID WP_263593623.1
Coordinates 2709865..2710131 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BRM3_RS12455 (BRM3_12455) 2705183..2708071 - 2889 WP_263593620.1 excinuclease ABC subunit UvrA -
BRM3_RS12460 (BRM3_12460) 2708193..2708966 + 774 WP_263593621.1 MBL fold metallo-hydrolase -
BRM3_RS12465 (BRM3_12465) 2709144..2709575 + 432 WP_263593622.1 VOC family protein -
BRM3_RS12470 (BRM3_12470) 2709606..2709863 - 258 WP_263595464.1 Txe/YoeB family addiction module toxin Toxin
BRM3_RS12475 (BRM3_12475) 2709865..2710131 - 267 WP_263593623.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
BRM3_RS12480 (BRM3_12480) 2710250..2711989 + 1740 WP_263593624.1 bifunctional 3'-5' exonuclease/DNA polymerase -
BRM3_RS12485 (BRM3_12485) 2712046..2712621 + 576 WP_263593625.1 dienelactone hydrolase family protein -
BRM3_RS12490 (BRM3_12490) 2712671..2714779 - 2109 WP_263593626.1 excinuclease ABC subunit UvrB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10232.50 Da        Isoelectric Point: 8.8926

>T260449 WP_263595464.1 NZ_CP107020:c2709863-2709606 [Brachybacterium huguangmaarense]
VLLVWSSSAWDDYLWWQSQDRKTLRRINTLIQDISRNGHDGIGKPEALKHDFAGYWSRRITDEHRLVYKIEGDEVRIAAC
RYHYR

Download         Length: 258 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9805.95 Da        Isoelectric Point: 4.4442

>AT260449 WP_263593623.1 NZ_CP107020:c2710131-2709865 [Brachybacterium huguangmaarense]
MKTLSYTESRARYAEVLDGVVADREEVVITRAGHEPVVIVSLDDYESLRETAYLMRSPANARRLLDAMEQLEGGRGARHE
LVDVDGDA

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References