Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 923371..923877 Replicon chromosome
Accession NZ_CP107020
Organism Brachybacterium huguangmaarense strain BRM-3

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag BRM3_RS04000 Protein ID WP_263594814.1
Coordinates 923371..923625 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag BRM3_RS04005 Protein ID WP_263594815.1
Coordinates 923626..923877 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BRM3_RS03980 (BRM3_03980) 919540..920493 + 954 WP_263594810.1 sugar ABC transporter permease -
BRM3_RS03985 (BRM3_03985) 920503..921432 + 930 WP_263594811.1 carbohydrate ABC transporter permease -
BRM3_RS03990 (BRM3_03990) 921429..922430 + 1002 WP_263594812.1 LacI family DNA-binding transcriptional regulator -
BRM3_RS03995 (BRM3_03995) 922462..923301 + 840 WP_263594813.1 MBL fold metallo-hydrolase -
BRM3_RS04000 (BRM3_04000) 923371..923625 - 255 WP_263594814.1 Txe/YoeB family addiction module toxin Toxin
BRM3_RS04005 (BRM3_04005) 923626..923877 - 252 WP_263594815.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
BRM3_RS04010 (BRM3_04010) 923989..925908 + 1920 WP_263594816.1 DNA helicase RecQ -
BRM3_RS04015 (BRM3_04015) 926148..926699 + 552 WP_263594817.1 universal stress protein -
BRM3_RS04020 (BRM3_04020) 926696..927178 + 483 WP_263594818.1 CrcB family protein -
BRM3_RS04025 (BRM3_04025) 927178..927552 + 375 WP_263594819.1 CrcB family protein -
BRM3_RS04030 (BRM3_04030) 927603..927857 - 255 WP_263594820.1 hypothetical protein -
BRM3_RS04035 (BRM3_04035) 928073..928789 + 717 WP_263595388.1 ethanolamine ammonia-lyase subunit EutC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-68)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9885.20 Da        Isoelectric Point: 7.2747

>T260448 WP_263594814.1 NZ_CP107020:c923625-923371 [Brachybacterium huguangmaarense]
VRLVWDRSAWEDYTSWQTSDRKILKRINTLLDACLREPTTGLGKPEPLKYGAQGAWSRRITEEHHLVYLVDGDDLVILQA
RYHY

Download         Length: 255 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9614.67 Da        Isoelectric Point: 4.8950

>AT260448 WP_263594815.1 NZ_CP107020:c923877-923626 [Brachybacterium huguangmaarense]
MSISASEARKTLFPLIERVNDDRDAVEIVSRKGNAVLMSADEYAAWQETAYLFRSPRNARRLLDAYERARDGRTEVHELD
RED

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References