Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2651389..2651598 Replicon chromosome
Accession NZ_CP104689
Organism Enterobacter hormaechei strain 2020CK-00376

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2651402..2651505 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2651389..2651598 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N5929_RS12620 (N5929_01175) 2647657..2649105 + 1449 WP_195207010.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
N5929_RS12625 (N5929_01170) 2649212..2649451 + 240 WP_003859885.1 YebV family protein -
N5929_RS12630 (N5929_01165) 2649486..2650130 - 645 WP_017693252.1 protein-serine/threonine phosphatase -
N5929_RS12635 (N5929_01160) 2650298..2651278 + 981 WP_023303891.1 VirK/YbjX family protein -
N5929_RS12640 (N5929_01155) 2651324..2651521 + 198 WP_017693250.1 hypothetical protein -
- 2651389..2651598 + 210 - - Antitoxin
- 2651402..2651505 - 104 - - Toxin
N5929_RS12645 (N5929_01150) 2651647..2651985 - 339 WP_003859787.1 YebY family protein -
N5929_RS12650 (N5929_01145) 2652002..2652871 - 870 WP_017693249.1 copper homeostasis membrane protein CopD -
N5929_RS12655 (N5929_01140) 2652873..2653244 - 372 WP_017384342.1 CopC domain-containing protein YobA -
N5929_RS12660 (N5929_01135) 2653382..2653612 + 231 WP_003859784.1 DNA polymerase III subunit theta -
N5929_RS12665 (N5929_01130) 2653724..2654374 + 651 WP_003859783.1 carbon-nitrogen hydrolase family protein -
N5929_RS12670 (N5929_01125) 2654399..2655061 + 663 WP_015570288.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T259006 NZ_CP104689:c2651505-2651402 [Enterobacter hormaechei]
GGCAAGGCGATTGAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 210 bp

>AT259006 NZ_CP104689:2651389-2651598 [Enterobacter hormaechei]
TTTTCAAGCAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGC
TAAAAGTTGGCATTAATGCAGGCTCAATCGCCTTGCCCTTTAAGAATAGATGACGACGTCAGGTTTTCCAGTCCACAGCA
AAAGTGGTCTGAAAAAAAGCGTCAGAACATCACTAAATGTGAAAAACCGC

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References