Detailed information of TA system TA258767

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): hok-sok/-
• Location: 2789504..2789729
• Replicon: chromosome
• Accession: NZ_CP104643
• Organism: Salmonella enterica strain 1020677

Toxin (Protein)

• Gene name: hokW
• Uniprot ID: S1ELB5
• Locus tag: N5930_RS13515
• Protein ID: WP_000813254.1
• Coordinates: 2789504..2789659 (-)
• Length: 52 a.a.

Antitoxin (RNA)

Gene name	sokW
Locus tag	-
Coordinates	2789671..2789729 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
N5930_RS13480	2784611..2784892	-	282	WP_000445513.1	phage holin family protein	-
N5930_RS13485	2784882..2785070	-	189	WP_001688615.1	putative holin	-
N5930_RS13490	2785064..2785387	-	324	Protein_2621	tellurite/colicin resistance protein	-
N5930_RS13495	2787558..2788094	-	537	WP_000640113.1	DUF1133 family protein	-
N5930_RS13500	2788091..2788381	-	291	WP_000774470.1	DUF1364 domain-containing protein	-
N5930_RS13505	2788381..2788980	-	600	WP_000940751.1	DUF1367 family protein	-
N5930_RS13510	2789043..2789213	-	171	WP_000734094.1	hypothetical protein	-
N5930_RS13515	2789504..2789659	-	156	WP_000813254.1	type I toxin-antitoxin system toxin HokD	Toxin
-	2789671..2789729	+	59	-	-	Antitoxin
N5930_RS13520	2790086..2791018	+	933	WP_000556389.1	hypothetical protein	-
N5930_RS13525	2791015..2791569	+	555	WP_001033796.1	hypothetical protein	-
N5930_RS13530	2791731..2792060	-	330	WP_001676916.1	DUF977 family protein	-
N5930_RS13535	2792104..2792151	-	48	Protein_2630	hypothetical protein	-
N5930_RS13540	2792333..2792800	+	468	WP_001227859.1	helix-turn-helix domain-containing protein	-
N5930_RS13545	2793185..2793340	+	156	WP_085981757.1	DUF1391 family protein	-
N5930_RS13550	2793448..2793969	-	522	WP_000004762.1	super-infection exclusion protein B	-
N5930_RS13555	2794407..2794628	+	222	WP_000560208.1	cell division protein FtsZ	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2784069..2795940	11871

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Hok/gef cell toxic protein (6-47)

Sequences

Toxin

Protein

• Length: 52 a.a.
• Molecular weight: 5736.89 Da
• Isoelectric Point: 6.1531

>T258767 WP_000813254.1 NZ_CP104643:c2789659-2789504 [Salmonella enterica]
MKQQKAMLIALIVICLTVIVTALVTRKDLCEVRIRTGQTEVAVFTAYEPEE

Nucleotide

• Length: 156 bp

Antitoxin

Nucleotide

• Length: 59 bp

>AT258767 NZ_CP104643:2789671-2789729 [Salmonella enterica]
CCTTGCCTTTCGGCACGTAAGAGGCTAACCTACATGTGCAAAGCATGAAATTGGCCTCA

Structures

Toxin

• AlphaFold DB: A0A4P7TMW0

Antitoxin