Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/MqsA(antitoxin)
Location 450212..450864 Replicon chromosome
Accession NZ_CP104497
Organism Ralstonia pseudosolanacearum strain Gj707

Toxin (Protein)


Gene name higB Uniprot ID A0A454TTN3
Locus tag NQS38_RS20040 Protein ID WP_038962847.1
Coordinates 450212..450556 (+) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag NQS38_RS20045 Protein ID WP_020425351.1
Coordinates 450553..450864 (+) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NQS38_RS20025 (NQS38_20025) 445908..447071 - 1164 WP_011003438.1 2-methylcitrate synthase -
NQS38_RS20030 (NQS38_20030) 447123..448019 - 897 WP_020425352.1 methylisocitrate lyase -
NQS38_RS20035 (NQS38_20035) 448212..450161 + 1950 WP_118888105.1 propionate catabolism operon regulatory protein PrpR -
NQS38_RS20040 (NQS38_20040) 450212..450556 + 345 WP_038962847.1 hypothetical protein Toxin
NQS38_RS20045 (NQS38_20045) 450553..450864 + 312 WP_020425351.1 transcriptional regulator Antitoxin
NQS38_RS20050 (NQS38_20050) 451004..451813 - 810 WP_043885575.1 DUF2242 domain-containing protein -
NQS38_RS20055 (NQS38_20055) 453100..454896 + 1797 WP_118912045.1 3'-5' exonuclease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 450212..489226 39014


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(41-91)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13227.94 Da        Isoelectric Point: 8.4489

>T258129 WP_038962847.1 NZ_CP104497:450212-450556 [Ralstonia pseudosolanacearum]
MDATFIELPPFQRLREHYLSDDEYRALQQELLARPDAGDVIKGTGGLRKLRFSDKRRGKGKRGGLRVIDYHWDGGGQFWM
FVVYDKGEADDLSSDERKVLARLLEQEVKARSER

Download         Length: 345 bp

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11619.65 Da        Isoelectric Point: 10.7132

>AT258129 WP_020425351.1 NZ_CP104497:450553-450864 [Ralstonia pseudosolanacearum]
MKRNLFAELKEGMDALAAEREGKMTLRKVKVRVLQPLDVTAEEIKAVRAAAHASQAVMARRLRVNVRTYQNWEQGTAKPN
TQAAVLIKLVEKHPETLQMLEAL

Download         Length: 312 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A454TTN3

Antitoxin

Source ID Structure

References