Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2134125..2134393 Replicon chromosome
Accession NZ_CP104274
Organism Escherichia coli strain Ec15103

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2134253..2134355 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2134125..2134393 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N2O69_RS10195 2130678..2131340 - 663 WP_000944258.1 exodeoxyribonuclease X -
N2O69_RS10200 2131364..2132020 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein YobB -
N2O69_RS10205 2132122..2132352 - 231 WP_000916763.1 DNA polymerase III subunit theta -
N2O69_RS10210 2132491..2132865 + 375 WP_000168747.1 CopC domain-containing protein YobA -
N2O69_RS10215 2132869..2133741 + 873 WP_000879311.1 copper homeostasis membrane protein CopD -
N2O69_RS10220 2133754..2134095 + 342 WP_000984819.1 YebY family protein -
- 2134125..2134393 - 269 - - Antitoxin
- 2134253..2134355 + 103 - - Toxin
N2O69_RS10225 2134490..2135146 + 657 WP_000812744.1 protein-serine/threonine phosphatase -
N2O69_RS10230 2135147..2135338 - 192 WP_024186842.1 YebW family protein -
N2O69_RS10235 2135443..2135679 - 237 WP_001295499.1 YebV family protein -
N2O69_RS10240 2135798..2137237 - 1440 WP_024186841.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T257439 NZ_CP104274:2134253-2134355 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT257439 NZ_CP104274:c2134393-2134125 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References