Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 2003092..2003667 Replicon chromosome
Accession NZ_CP104215
Organism Burkholderia gladioli strain ZN-S4

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NYZ96_RS27370 Protein ID WP_036054553.1
Coordinates 2003380..2003667 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A560UNM0
Locus tag NYZ96_RS27365 Protein ID WP_036030606.1
Coordinates 2003092..2003376 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NYZ96_RS27345 (NYZ96_27345) 1998172..1999455 - 1284 WP_260531441.1 4-aminobutyrate--2-oxoglutarate transaminase -
NYZ96_RS27350 (NYZ96_27350) 1999591..2001246 + 1656 WP_172877029.1 PLP-dependent aminotransferase family protein -
NYZ96_RS27355 (NYZ96_27355) 2001384..2002559 + 1176 WP_046582019.1 ABC transporter substrate-binding protein -
NYZ96_RS27360 (NYZ96_27360) 2002708..2003034 + 327 WP_186016973.1 hypothetical protein -
NYZ96_RS27365 (NYZ96_27365) 2003092..2003376 - 285 WP_036030606.1 putative addiction module antidote protein Antitoxin
NYZ96_RS27370 (NYZ96_27370) 2003380..2003667 - 288 WP_036054553.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NYZ96_RS27375 (NYZ96_27375) 2003800..2004738 - 939 WP_046582023.1 ketopantoate reductase family protein -
NYZ96_RS27380 (NYZ96_27380) 2004896..2005366 + 471 WP_013689305.1 Lrp/AsnC family transcriptional regulator -
NYZ96_RS27385 (NYZ96_27385) 2005410..2006246 - 837 WP_036054549.1 DMT family transporter -
NYZ96_RS27390 (NYZ96_27390) 2006465..2007526 + 1062 WP_105827369.1 selenide, water dikinase SelD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(5-94)

Antitoxin

Uncharacterized protein HI1420

(11-89)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10959.72 Da        Isoelectric Point: 10.4966

>T257421 WP_036054553.1 NZ_CP104215:c2003667-2003380 [Burkholderia gladioli]
MLRSSEFTNWLSSLRDQRGKARIAARLISAQLGNFGEYRVIGEGVREMKVDFGPGYRIYYVRRAEIVYVLLCGGDKSTQK
KDIKRALQMARELKE

Download         Length: 288 bp

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10072.47 Da        Isoelectric Point: 5.0484

>AT257421 WP_036030606.1 NZ_CP104215:c2003376-2003092 [Burkholderia gladioli]
MPDYAEFDAADYLDNDETVAEFLAVAAEDPDPAVFLAAVAAVARARGMTKVASEAGLGRVTLHKALTPGAHPRYETVQKI
LRSLGLRMTFTVAH

Download         Length: 285 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A560UNM0

References