Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 112298..112940 Replicon chromosome
Accession NZ_CP104215
Organism Burkholderia gladioli strain ZN-S4

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NYZ96_RS19270 Protein ID WP_105851412.1
Coordinates 112298..112720 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NYZ96_RS19275 Protein ID WP_105827555.1
Coordinates 112707..112940 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NYZ96_RS19250 (NYZ96_19250) 108098..109471 + 1374 WP_046582154.1 L-fucose:H+ symporter permease -
NYZ96_RS19255 (NYZ96_19255) 109474..110556 + 1083 WP_105827531.1 aldose 1-epimerase family protein -
NYZ96_RS19260 (NYZ96_19260) 110576..111346 - 771 WP_025101959.1 DNA-binding transcriptional repressor DeoR -
NYZ96_RS19265 (NYZ96_19265) 111496..112176 + 681 WP_105851413.1 deoxyribose-phosphate aldolase -
NYZ96_RS19270 (NYZ96_19270) 112298..112720 - 423 WP_105851412.1 type II toxin-antitoxin system VapC family toxin Toxin
NYZ96_RS19275 (NYZ96_19275) 112707..112940 - 234 WP_105827555.1 DNA-binding protein Antitoxin
NYZ96_RS19280 (NYZ96_19280) 113256..114245 - 990 WP_105850350.1 LysR substrate-binding domain-containing protein -
NYZ96_RS19285 (NYZ96_19285) 114866..116599 + 1734 WP_241163391.1 AMP-binding protein -
NYZ96_RS19290 (NYZ96_19290) 116724..116972 + 249 WP_013690725.1 acyl carrier protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 15707.01 Da        Isoelectric Point: 9.5579

>T257420 WP_105851412.1 NZ_CP104215:c112720-112298 [Burkholderia gladioli]
MYLIDTNVVSEVRKRDRADKGVMAFFRQAARDDAGLYLSVVTVGELRRGVEIIRHRGDKSQATRLANWLDGVLREFAENI
LVVDKEIGQMWGYLRVPRSEHSLDKVIAATALIHDLTVVTRNVDDFAGTGARVLNPFKGP

Download         Length: 423 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8512.67 Da        Isoelectric Point: 5.5741

>AT257420 WP_105827555.1 NZ_CP104215:c112940-112707 [Burkholderia gladioli]
MANLLVRNVDEMLVQILRERAAAHGHSAEAEHRAILARALREPQRKTFAQVLMGMPNVGSDVDFARVDDGEAANVFD

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References