Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/- |
| Location | 3084868..3086145 | Replicon | chromosome |
| Accession | NZ_CP104214 | ||
| Organism | Burkholderia gladioli strain ZN-S4 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | NYZ96_RS13750 | Protein ID | WP_105852005.1 |
| Coordinates | 3084868..3085452 (-) | Length | 195 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | NYZ96_RS13755 | Protein ID | WP_105827486.1 |
| Coordinates | 3085555..3086145 (-) | Length | 197 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NYZ96_RS13725 (NYZ96_13725) | 3080507..3081064 | + | 558 | WP_241163527.1 | DUF302 domain-containing protein | - |
| NYZ96_RS13730 (NYZ96_13730) | 3081189..3082151 | - | 963 | WP_105852003.1 | AraC family transcriptional regulator | - |
| NYZ96_RS13735 (NYZ96_13735) | 3082345..3083160 | - | 816 | WP_181159703.1 | lytic transglycosylase domain-containing protein | - |
| NYZ96_RS13740 (NYZ96_13740) | 3083565..3084302 | - | 738 | WP_146127782.1 | hypothetical protein | - |
| NYZ96_RS13750 (NYZ96_13750) | 3084868..3085452 | - | 585 | WP_105852005.1 | HD domain-containing protein | Toxin |
| NYZ96_RS13755 (NYZ96_13755) | 3085555..3086145 | - | 591 | WP_105827486.1 | helix-turn-helix transcriptional regulator | Antitoxin |
| NYZ96_RS13760 (NYZ96_13760) | 3086297..3086560 | - | 264 | WP_013698802.1 | PAAR domain-containing protein | - |
| NYZ96_RS13765 (NYZ96_13765) | 3086627..3087061 | - | 435 | WP_105852006.1 | hypothetical protein | - |
| NYZ96_RS13770 (NYZ96_13770) | 3087105..3089120 | - | 2016 | WP_260531247.1 | VC_2705 family sodium/solute symporter | - |
| NYZ96_RS13775 (NYZ96_13775) | 3089114..3089551 | - | 438 | WP_105852007.1 | DUF4212 domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 195 a.a. Molecular weight: 21529.24 Da Isoelectric Point: 5.0097
>T257419 WP_105852005.1 NZ_CP104214:c3085452-3084868 [Burkholderia gladioli]
MDDALIDARLDFLRGCERLKDVLRSGHTSGGRRESTAEHSWRLALMAMVLMDQLGEVDPGRVLELCLVHDLGEALGGDVP
APEQAPGSDKDAAERRDLLRLGDALDAPMRERIVALWDEYARAATPEARAVKALDKIETILQHTQGENPPDFDYAFNLSY
GQAHTRKVPALQRFRERVDEATRERMTRAGGPSG
MDDALIDARLDFLRGCERLKDVLRSGHTSGGRRESTAEHSWRLALMAMVLMDQLGEVDPGRVLELCLVHDLGEALGGDVP
APEQAPGSDKDAAERRDLLRLGDALDAPMRERIVALWDEYARAATPEARAVKALDKIETILQHTQGENPPDFDYAFNLSY
GQAHTRKVPALQRFRERVDEATRERMTRAGGPSG
Download Length: 585 bp
Antitoxin
Download Length: 197 a.a. Molecular weight: 21512.38 Da Isoelectric Point: 8.7083
>AT257419 WP_105827486.1 NZ_CP104214:c3086145-3085555 [Burkholderia gladioli]
MKPISSNQATTTSLPPSALACSPGASLRRWRTLRRIKQEHAAALFGVSQSTISRWEAGTQAVSHEELRRIEACLSARLDS
AADRALERLVSHHTRPVHLVCDLTHRLLACSTPRAAEFAAPLSSLMGASLWPFATAEIVAREQSLRDAGWHDHPAPSIEF
DTGSNDSPQVPIRASRCRWTRFTLSDGTLARLVETL
MKPISSNQATTTSLPPSALACSPGASLRRWRTLRRIKQEHAAALFGVSQSTISRWEAGTQAVSHEELRRIEACLSARLDS
AADRALERLVSHHTRPVHLVCDLTHRLLACSTPRAAEFAAPLSSLMGASLWPFATAEIVAREQSLRDAGWHDHPAPSIEF
DTGSNDSPQVPIRASRCRWTRFTLSDGTLARLVETL
Download Length: 591 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|