Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-VapI
Location 5769125..5769736 Replicon chromosome
Accession NZ_CP104174
Organism Bradyrhizobium sp. CB1015

Toxin (Protein)


Gene name graT Uniprot ID -
Locus tag N2604_RS26905 Protein ID WP_260371149.1
Coordinates 5769452..5769736 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID A0A150U781
Locus tag N2604_RS26900 Protein ID WP_063195082.1
Coordinates 5769125..5769442 (-) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N2604_RS26880 (N2604_26880) 5764689..5764952 - 264 WP_025036968.1 EscU/YscU/HrcU family type III secretion system export apparatus switch protein -
N2604_RS26885 (N2604_26885) 5764949..5766583 - 1635 WP_260371146.1 flagellar hook-length control protein FliK -
N2604_RS26890 (N2604_26890) 5766639..5767433 - 795 WP_260371147.1 ATP12 family protein -
N2604_RS26895 (N2604_26895) 5767911..5769128 - 1218 WP_260371148.1 RluA family pseudouridine synthase -
N2604_RS26900 (N2604_26900) 5769125..5769442 - 318 WP_063195082.1 HigA family addiction module antitoxin Antitoxin
N2604_RS26905 (N2604_26905) 5769452..5769736 - 285 WP_260371149.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N2604_RS26910 (N2604_26910) 5769794..5771128 - 1335 WP_260371150.1 replication-associated recombination protein A -
N2604_RS26915 (N2604_26915) 5771125..5772531 - 1407 WP_260371151.1 DegQ family serine endoprotease -
N2604_RS26920 (N2604_26920) 5772848..5774461 + 1614 WP_260371152.1 OprO/OprP family phosphate-selective porin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(4-94)

Antitoxin

Toxin-antitoxin system, antidote protein, HigA

(3-80)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10633.93 Da        Isoelectric Point: 6.4615

>T257371 WP_260371149.1 NZ_CP104174:c5769736-5769452 [Bradyrhizobium sp. CB1015]
MIVSYRDKRTERFAAGQHVKEFSGFARQAETRLDRLDAATSLADLAALPGNRLEALKGDRAGQFSIRINDQWRICFNWPE
GSPGPIDVEIVDYH

Download         Length: 285 bp

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11645.29 Da        Isoelectric Point: 10.5812

>AT257371 WP_063195082.1 NZ_CP104174:c5769442-5769125 [Bradyrhizobium sp. CB1015]
MPRTPIHPGEQLAEELRELGITAAELSRQIDVPVNRITGIINGQRGITADTALRLGHWFGTSPQFWMNLQQQYELRLAEK
EVGAQVASLPRRASAQSTRKLGKTA

Download         Length: 318 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A150U781

References