Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 1133425..1134131 Replicon chromosome
Accession NZ_CP104173
Organism Bradyrhizobium sp. CB1024

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag N2605_RS05345 Protein ID WP_260345991.1
Coordinates 1133425..1133850 (-) Length 142 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag N2605_RS05350 Protein ID WP_260345992.1
Coordinates 1133847..1134131 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N2605_RS05320 (N2605_05320) 1130097..1130504 + 408 WP_036013863.1 acyl-CoA thioesterase -
N2605_RS05325 (N2605_05325) 1130737..1130928 + 192 WP_036013862.1 hypothetical protein -
N2605_RS05330 (N2605_05330) 1131178..1131630 - 453 WP_036013866.1 nuclear transport factor 2 family protein -
N2605_RS05335 (N2605_05335) 1131783..1132469 + 687 WP_260345990.1 HAD-IA family hydrolase -
N2605_RS05340 (N2605_05340) 1132576..1133421 + 846 WP_036013860.1 DeoR/GlpR family DNA-binding transcription regulator -
N2605_RS05345 (N2605_05345) 1133425..1133850 - 426 WP_260345991.1 type II toxin-antitoxin system VapC family toxin Toxin
N2605_RS05350 (N2605_05350) 1133847..1134131 - 285 WP_260345992.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
N2605_RS05355 (N2605_05355) 1134359..1135909 + 1551 WP_260345993.1 glycerol-3-phosphate dehydrogenase -
N2605_RS05360 (N2605_05360) 1135906..1136982 + 1077 WP_057026248.1 ABC transporter ATP-binding protein -
N2605_RS05365 (N2605_05365) 1136997..1138082 + 1086 WP_036013850.1 ABC transporter ATP-binding protein -
N2605_RS05370 (N2605_05370) 1138082..1139056 + 975 WP_036013849.1 sugar ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-123)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(15-76)


Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 15566.90 Da        Isoelectric Point: 4.9055

>T257368 WP_260345991.1 NZ_CP104173:c1133850-1133425 [Bradyrhizobium sp. CB1024]
MNLLLDTNVLSEVQRPAPSPKVVGWLDRIDEDRAFISVASIAELRRGIALLEDGRRRTALAVWLAHDLPARFAERVLPID
QTVAERWGDLMAQSRKSGVALSVMDGFFAATALVNDLTLVTRNVKDFAAFGVPLLNPWDDA

Download         Length: 426 bp

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10421.83 Da        Isoelectric Point: 7.2057

>AT257368 WP_260345992.1 NZ_CP104173:c1134131-1133847 [Bradyrhizobium sp. CB1024]
MVNRNAEPDALPTKDSWTLANAKARLSEVLDRAQTGPQVITRHGKPNAVIVSVEEWARKTARKGTLAEFLLASPLRGVDL
ELDRLHDTPRDEVP

Download         Length: 285 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References