Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2523706..2523890 Replicon chromosome
Accession NZ_CP103850
Organism Staphylococcus aureus strain NRL 02/947

Toxin (Protein)


Gene name SprA2 Uniprot ID Q2FVI9
Locus tag NYF25_RS12690 Protein ID WP_000482650.1
Coordinates 2523783..2523890 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2523706..2523766 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NYF25_RS12675 2519236..2519403 - 168 WP_001790576.1 hypothetical protein -
NYF25_RS12680 2519634..2521367 - 1734 WP_000486494.1 ABC transporter ATP-binding protein -
NYF25_RS12685 2521392..2523155 - 1764 WP_001064838.1 ABC transporter ATP-binding protein -
- 2523706..2523766 + 61 - - Antitoxin
NYF25_RS12690 2523783..2523890 - 108 WP_000482650.1 type I toxin-antitoxin system Fst family toxin Toxin
NYF25_RS12695 2524024..2524410 - 387 WP_000779358.1 flippase GtxA -
NYF25_RS12700 2524678..2525820 + 1143 WP_001176863.1 glycerate kinase -
NYF25_RS12705 2525880..2526539 + 660 WP_000831298.1 membrane protein -
NYF25_RS12710 2526721..2527932 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
NYF25_RS12715 2528055..2528528 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T256797 WP_000482650.1 NZ_CP103850:c2523890-2523783 [Staphylococcus aureus]
MFNLLINIMTSAISGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT256797 NZ_CP103850:2523706-2523766 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2C9TTS8

Antitoxin

Download structure file

References