Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2331624..2331892 Replicon chromosome
Accession NZ_CP103589
Organism Escherichia coli strain 4750

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2331752..2331854 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2331624..2331892 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5T00_RS11030 2328177..2328839 - 663 WP_000944258.1 exodeoxyribonuclease X -
M5T00_RS11035 2328863..2329519 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein YobB -
M5T00_RS11040 2329621..2329851 - 231 WP_000916763.1 DNA polymerase III subunit theta -
M5T00_RS11045 2329990..2330364 + 375 WP_000168747.1 CopC domain-containing protein YobA -
M5T00_RS11050 2330368..2331240 + 873 WP_000879311.1 copper homeostasis membrane protein CopD -
M5T00_RS11055 2331253..2331594 + 342 WP_000984819.1 YebY family protein -
- 2331624..2331892 - 269 - - Antitoxin
- 2331752..2331854 + 103 - - Toxin
M5T00_RS11060 2331989..2332645 + 657 WP_000812744.1 protein-serine/threonine phosphatase -
M5T00_RS11065 2332646..2332837 - 192 WP_024186842.1 YebW family protein -
M5T00_RS11070 2332942..2333178 - 237 WP_001295499.1 YebV family protein -
M5T00_RS11075 2333297..2334736 - 1440 WP_024186841.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T255699 NZ_CP103589:2331752-2331854 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT255699 NZ_CP103589:c2331892-2331624 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References