Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2158954..2159222 Replicon chromosome
Accession NZ_CP103465
Organism Escherichia coli O25b:H4-ST131 strain 5392

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2159082..2159184 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2158954..2159222 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M5T42_RS10275 2155507..2156169 - 663 WP_000944256.1 exodeoxyribonuclease X -
M5T42_RS10280 2156193..2156849 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein YobB -
M5T42_RS10285 2156951..2157181 - 231 WP_000916763.1 DNA polymerase III subunit theta -
M5T42_RS10290 2157320..2157694 + 375 WP_000168747.1 CopC domain-containing protein YobA -
M5T42_RS10295 2157698..2158570 + 873 WP_000879317.1 copper homeostasis membrane protein CopD -
M5T42_RS10300 2158583..2158924 + 342 WP_000976472.1 YebY family protein -
- 2158954..2159222 - 269 - - Antitoxin
- 2159082..2159184 + 103 - - Toxin
M5T42_RS10305 2159319..2159975 + 657 WP_000812745.1 protein-serine/threonine phosphatase -
M5T42_RS10310 2159976..2160167 - 192 WP_001296140.1 YebW family protein -
M5T42_RS10315 2160272..2160508 - 237 WP_001295499.1 YebV family protein -
M5T42_RS10320 2160625..2162064 - 1440 WP_001296139.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T255079 NZ_CP103465:2159082-2159184 [Escherichia coli O25b:H4-ST131]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT255079 NZ_CP103465:c2159222-2158954 [Escherichia coli O25b:H4-ST131]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATATTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References