Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | hicAB/- |
Location | 662093..662676 | Replicon | chromosome |
Accession | NZ_CP103345 | ||
Organism | Brucella anthropi strain CGMCC 1.17299 |
Toxin (Protein)
Gene name | hicA | Uniprot ID | A0A6I0DCD4 |
Locus tag | NW321_RS03090 | Protein ID | WP_040129739.1 |
Coordinates | 662422..662676 (-) | Length | 85 a.a. |
Antitoxin (Protein)
Gene name | hicB | Uniprot ID | A0A1T4LVA5 |
Locus tag | NW321_RS03085 | Protein ID | WP_012090880.1 |
Coordinates | 662093..662425 (-) | Length | 111 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
NW321_RS03045 (NW321_03045) | 657562..657708 | + | 147 | WP_158304318.1 | hypothetical protein | - |
NW321_RS03050 (NW321_03050) | 657738..657922 | + | 185 | Protein_603 | IS5/IS1182 family transposase | - |
NW321_RS03055 (NW321_03055) | 658566..658880 | - | 315 | WP_041545288.1 | BrnA antitoxin family protein | - |
NW321_RS03060 (NW321_03060) | 658880..659164 | - | 285 | WP_158304319.1 | hypothetical protein | - |
NW321_RS03065 (NW321_03065) | 659343..660524 | + | 1182 | WP_012090877.1 | Fic family protein | - |
NW321_RS03070 (NW321_03070) | 660801..660959 | + | 159 | WP_259030353.1 | PIN domain-containing protein | - |
NW321_RS03075 (NW321_03075) | 660956..661210 | + | 255 | WP_125301843.1 | toxin-antitoxin system HicB family antitoxin | - |
NW321_RS03080 (NW321_03080) | 661512..661938 | + | 427 | Protein_609 | type IV secretory system conjugative DNA transfer family protein | - |
NW321_RS03085 (NW321_03085) | 662093..662425 | - | 333 | WP_012090880.1 | type II toxin-antitoxin system HicB family antitoxin | Antitoxin |
NW321_RS03090 (NW321_03090) | 662422..662676 | - | 255 | WP_040129739.1 | type II toxin-antitoxin system HicA family toxin | Toxin |
NW321_RS03095 (NW321_03095) | 662690..662965 | - | 276 | WP_235915181.1 | hypothetical protein | - |
NW321_RS03100 (NW321_03100) | 663108..664001 | + | 894 | WP_012090883.1 | MurR/RpiR family transcriptional regulator | - |
NW321_RS03105 (NW321_03105) | 663982..665853 | + | 1872 | WP_094513471.1 | dipeptide ABC transporter ATP-binding protein | - |
NW321_RS03110 (NW321_03110) | 665873..667405 | + | 1533 | WP_040129733.1 | glutathione ABC transporter substrate-binding protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Integrative and Conjugative Element | - | - | 647369..729307 | 81938 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A6I0DCD4 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A1T4LVA5 |