Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/MazF(toxin)
Location 274583..275222 Replicon chromosome
Accession NZ_CP103291
Organism Peribacillus frigoritolerans strain NS1

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag NWE71_RS01420 Protein ID WP_034306610.1
Coordinates 274872..275222 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag NWE71_RS01415 Protein ID WP_034306380.1
Coordinates 274583..274864 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NWE71_RS01395 270722..271312 - 591 WP_057277208.1 rhomboid family intramembrane serine protease -
NWE71_RS01400 271420..271770 + 351 WP_053537119.1 holo-ACP synthase -
NWE71_RS01405 272013..273017 + 1005 WP_095396324.1 outer membrane lipoprotein carrier protein LolA -
NWE71_RS01410 273235..274422 + 1188 WP_258832640.1 alanine racemase -
NWE71_RS01415 274583..274864 + 282 WP_034306380.1 antitoxin EndoAI Antitoxin
NWE71_RS01420 274872..275222 + 351 WP_034306610.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
NWE71_RS01425 275639..276466 + 828 WP_048682050.1 RsbT co-antagonist protein RsbRA -
NWE71_RS01430 276469..276825 + 357 WP_048682053.1 STAS domain-containing protein -
NWE71_RS01435 276829..277230 + 402 WP_048682056.1 anti-sigma regulatory factor -
NWE71_RS01440 277240..278250 + 1011 WP_258832641.1 PP2C family protein-serine/threonine phosphatase -
NWE71_RS01445 278310..278642 + 333 WP_034306369.1 anti-sigma factor antagonist -
NWE71_RS01450 278639..279112 + 474 WP_034306366.1 anti-sigma B factor RsbW -
NWE71_RS01455 279090..279878 + 789 WP_258832642.1 RNA polymerase sigma factor SigB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-113)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12955.06 Da        Isoelectric Point: 7.2029

>T254858 WP_034306610.1 NZ_CP103291:274872-275222 [Peribacillus frigoritolerans]
IVVKRGDVYFADLSPVVGSEQGGTRPVLILQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEINAKKYGFERDSVILLEQI
RTIDKQRLTDKITHLDEPMMQKVNEALQISLGLIEF

Download         Length: 351 bp

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10713.13 Da        Isoelectric Point: 5.9054

>AT254858 WP_034306380.1 NZ_CP103291:274583-274864 [Peribacillus frigoritolerans]
VSESSATREILIRLPQNFLTELDGYASEENVNRSEFIYRATKMYLRERKKKEFRESMKRGYIEMAAINLTIASEAFQAEF
EAGHCVERLVSGG

Download         Length: 282 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References