Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2447091..2447275 Replicon chromosome
Accession NZ_CP102953
Organism Staphylococcus aureus strain 32-T-13

Toxin (Protein)


Gene name SprA2 Uniprot ID Q2FVI9
Locus tag NW977_RS12120 Protein ID WP_000482650.1
Coordinates 2447168..2447275 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2447091..2447151 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NW977_RS12110 (NW977_12110) 2443019..2444752 - 1734 WP_258414933.1 ABC transporter ATP-binding protein -
NW977_RS12115 (NW977_12115) 2444777..2446540 - 1764 WP_258414934.1 ABC transporter ATP-binding protein -
- 2447091..2447151 + 61 - - Antitoxin
NW977_RS12120 (NW977_12120) 2447168..2447275 - 108 WP_000482650.1 type I toxin-antitoxin system Fst family toxin Toxin
NW977_RS12125 (NW977_12125) 2447409..2447795 - 387 WP_000779358.1 flippase GtxA -
NW977_RS12130 (NW977_12130) 2448063..2449205 + 1143 WP_001176863.1 glycerate kinase -
NW977_RS12135 (NW977_12135) 2449265..2449924 + 660 WP_000831298.1 membrane protein -
NW977_RS12140 (NW977_12140) 2450106..2451317 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
NW977_RS12145 (NW977_12145) 2451440..2451913 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4011.78 Da        Isoelectric Point: 11.0582

>T254604 WP_000482650.1 NZ_CP102953:c2447275-2447168 [Staphylococcus aureus]
MFNLLINIMTSAISGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

Antitoxin


Download         Length: 61 bp

>AT254604 NZ_CP102953:2447091-2447151 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2C9TTS8

Antitoxin

Download structure file

References