Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vagCD/VagC(antitoxin)
Location 1981956..1982380 Replicon chromosome
Accession NZ_CP102462
Organism Burkholderia contaminans strain NML151013

Toxin (Protein)


Gene name vagD Uniprot ID -
Locus tag NUJ29_RS09270 Protein ID WP_223274361.1
Coordinates 1982219..1982380 (+) Length 54 a.a.

Antitoxin (Protein)


Gene name vagC Uniprot ID -
Locus tag NUJ29_RS09265 Protein ID WP_105815832.1
Coordinates 1981956..1982222 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NUJ29_RS09250 (NUJ29_09250) 1977512..1979764 + 2253 WP_105815834.1 TonB-dependent siderophore receptor -
NUJ29_RS09255 (NUJ29_09255) 1979851..1980690 + 840 WP_105815917.1 formyltransferase family protein -
NUJ29_RS09260 (NUJ29_09260) 1980690..1981706 + 1017 WP_105815833.1 GNAT family N-acetyltransferase -
NUJ29_RS09265 (NUJ29_09265) 1981956..1982222 + 267 WP_105815832.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
NUJ29_RS09270 (NUJ29_09270) 1982219..1982380 + 162 WP_223274361.1 type II toxin-antitoxin system VapC family toxin Toxin
NUJ29_RS09275 (NUJ29_09275) 1982408..1982635 + 228 WP_224756031.1 hypothetical protein -
NUJ29_RS09280 (NUJ29_09280) 1982684..1982923 - 240 Protein_1807 nucleotidyltransferase -
NUJ29_RS09285 (NUJ29_09285) 1982937..1984007 - 1071 WP_105815831.1 type IV toxin-antitoxin system AbiEi family antitoxin -
NUJ29_RS09290 (NUJ29_09290) 1984349..1985512 + 1164 WP_039358627.1 M20 aminoacylase family protein -
NUJ29_RS09295 (NUJ29_09295) 1985538..1985705 + 168 WP_105815830.1 type II toxin-antitoxin system RelE/ParE family toxin -
NUJ29_RS09300 (NUJ29_09300) 1985776..1987080 - 1305 WP_105815829.1 cobyrinate a,c-diamide synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

SpoVT-AbrB domain

(7-55)


Sequences

Toxin        


Download         Length: 54 a.a.        Molecular weight: 5903.95 Da        Isoelectric Point: 8.5349

>T253687 WP_223274361.1 NZ_CP102462:1982219-1982380 [Burkholderia contaminans]
VTTLYMLDTSICSFIMRERPPVVLSRLQSCVNAQHRIVVSAITYAEMRFGAAG

Download         Length: 162 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9712.94 Da        Isoelectric Point: 4.4819

>AT253687 WP_105815832.1 NZ_CP102462:1981956-1982222 [Burkholderia contaminans]
MRTVSIFKNARNQAIRIPKDMEFEGVTELEIRREGDTLLLRPVRPTWLSFASEPPADADFLAERPAVIEPGRFDLSDGGG
AAPTESGQ

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References