253300

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2000328..2000473 Replicon chromosome
Accession NZ_CP102186
Organism Klebsiella pneumoniae strain S234

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2000364..2000466 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2000328..2000473 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NQZ63_RS09790 (NQZ63_09790) 1995458..1997518 + 2061 WP_004151449.1 oligopeptidase B -
NQZ63_RS09795 (NQZ63_09795) 1997522..1998181 - 660 WP_002911407.1 exodeoxyribonuclease X -
NQZ63_RS09800 (NQZ63_09800) 1998260..1998490 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NQZ63_RS09805 (NQZ63_09805) 1998603..1998977 + 375 WP_004151448.1 CopC domain-containing protein YobA -
NQZ63_RS09810 (NQZ63_09810) 1998981..1999850 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
NQZ63_RS09815 (NQZ63_09815) 1999867..2000205 + 339 WP_002911404.1 YebY family protein -
- 2000328..2000473 - 146 - - Antitoxin
- 2000364..2000466 + 103 - - Toxin
NQZ63_RS09820 (NQZ63_09820) 2000841..2000984 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
NQZ63_RS09825 (NQZ63_09825) 2001089..2002057 - 969 WP_004151446.1 VirK/YbjX family protein -
NQZ63_RS09830 (NQZ63_09830) 2002214..2002867 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
NQZ63_RS09835 (NQZ63_09835) 2002864..2003055 - 192 WP_002911395.1 YebW family protein -
NQZ63_RS09840 (NQZ63_09840) 2003153..2003392 - 240 WP_002911393.1 YebV family protein -
NQZ63_RS09845 (NQZ63_09845) 2003508..2004941 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T253300 NZ_CP102186:2000364-2000466 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT253300 NZ_CP102186:c2000473-2000328 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References