Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-PHD
Location 3813929..3814596 Replicon chromosome
Accession NZ_CP101989
Organism Cellulomonas wangsupingiae strain zg-Y908

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NP075_RS17525 Protein ID WP_227563378.1
Coordinates 3813929..3814321 (-) Length 131 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NP075_RS17530 Protein ID WP_227563379.1
Coordinates 3814324..3814596 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NP075_RS17505 (NP075_17505) 3809450..3810197 - 748 Protein_3438 SDR family oxidoreductase -
NP075_RS17510 (NP075_17510) 3810631..3812061 - 1431 WP_227563375.1 ADP-ribosylglycohydrolase family protein -
NP075_RS17515 (NP075_17515) 3812411..3812974 + 564 WP_227563376.1 DUF6318 family protein -
NP075_RS17520 (NP075_17520) 3812971..3813867 + 897 WP_227563377.1 PKD domain-containing protein -
NP075_RS17525 (NP075_17525) 3813929..3814321 - 393 WP_227563378.1 type II toxin-antitoxin system VapC family toxin Toxin
NP075_RS17530 (NP075_17530) 3814324..3814596 - 273 WP_227563379.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
NP075_RS17535 (NP075_17535) 3814708..3814887 - 180 WP_227563380.1 hypothetical protein -
NP075_RS17540 (NP075_17540) 3814986..3815429 - 444 WP_227563381.1 hypothetical protein -
NP075_RS17545 (NP075_17545) 3815810..3816079 - 270 WP_227563382.1 alpha-mannosidase -
NP075_RS17550 (NP075_17550) 3816110..3816718 - 609 WP_227563383.1 hypothetical protein -
NP075_RS17555 (NP075_17555) 3816832..3819147 - 2316 WP_256791285.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3783463..3816835 33372


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-119)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-40)


Sequences

Toxin        


Download         Length: 131 a.a.        Molecular weight: 13805.79 Da        Isoelectric Point: 4.4687

>T253072 WP_227563378.1 NZ_CP101989:c3814321-3813929 [Cellulomonas wangsupingiae]
VAYYLDTSALVKLVVEEAETPALREWWRSHGTTPVACDLVRTELMRAVRRAAPEAAVQAHAVLDGLVLLSVTSRVCDAAG
RLEPATLRSLDAIHLAAALELGDDLEGIVTYDDRLAEAAVAYGVAVVAPA

Download         Length: 393 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 9225.46 Da        Isoelectric Point: 11.5657

>AT253072 WP_227563379.1 NZ_CP101989:c3814596-3814324 [Cellulomonas wangsupingiae]
MATIGIRELKQNASAAVARAASGETLTVTDRGRPTAQLSPLPSSPLARLLTSGAARPARTDLAALPEPRPAAGGRPSLSD
ALAELRADER

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References