Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-dinJ/YafQ-RelB
Location 1989531..1990062 Replicon chromosome
Accession NZ_CP101739
Organism Stutzerimonas stutzeri strain J15

Toxin (Protein)


Gene name relE Uniprot ID W2D823
Locus tag NPN27_RS09420 Protein ID WP_011282522.1
Coordinates 1989781..1990062 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID W2D9V6
Locus tag NPN27_RS09415 Protein ID WP_020303033.1
Coordinates 1989531..1989794 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NPN27_RS09390 (NPN27_09390) 1984565..1984792 + 228 Protein_1848 integrase -
NPN27_RS09395 (NPN27_09395) 1984986..1985789 - 804 WP_013983152.1 IS21-like element ISPst3 family helper ATPase IstB -
NPN27_RS09400 (NPN27_09400) 1985782..1987281 - 1500 WP_256519138.1 IS21-like element ISPst3 family transposase -
NPN27_RS09405 (NPN27_09405) 1987397..1988731 - 1335 Protein_1851 IS481 family transposase -
NPN27_RS09410 (NPN27_09410) 1988736..1989311 - 576 WP_032905003.1 recombinase family protein -
NPN27_RS09415 (NPN27_09415) 1989531..1989794 + 264 WP_020303033.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
NPN27_RS09420 (NPN27_09420) 1989781..1990062 + 282 WP_011282522.1 type II toxin-antitoxin system YafQ family toxin Toxin
NPN27_RS09425 (NPN27_09425) 1990282..1990529 + 248 Protein_1855 hypothetical protein -
NPN27_RS09430 (NPN27_09430) 1990619..1992244 - 1626 WP_256519045.1 methyl-accepting chemotaxis protein -
NPN27_RS09435 (NPN27_09435) 1992547..1993404 - 858 WP_057386701.1 phosphate/phosphite/phosphonate ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1979364..1996427 17063


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-84)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10710.20 Da        Isoelectric Point: 9.6866

>T252583 WP_011282522.1 NZ_CP101739:1989781-1990062 [Stutzerimonas stutzeri]
MRTIEQTSRFKRDYKREAKGPHRQTLASDFIAVVTALANNQPLAEKHRDHALTGDWKDHRDCHIKPDLVLIYRKPDDAVL
QLVRLGSHSELGL

Download         Length: 282 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9471.95 Da        Isoelectric Point: 4.8096

>AT252583 WP_020303033.1 NZ_CP101739:1989531-1989794 [Stutzerimonas stutzeri]
MSANAVVRARIDEHIKEEATVVLAAMGLTVSDAFRIMLTRVAREKALPFEPLIPNATTIEAMKEARRGGLKSFASVEDLM
ADLNADD

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0W0N2T9

Antitoxin

Source ID Structure
AlphaFold DB A0A0W0N2R7

References