Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2021231..2021502 Replicon chromosome
Accession NZ_CP101615
Organism Escherichia coli strain DC71

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2021361..2021464 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2021231..2021502 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NOF56_RS09690 2017786..2018448 - 663 WP_000944256.1 exodeoxyribonuclease X -
NOF56_RS09695 2018472..2019128 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
NOF56_RS09700 2019230..2019460 - 231 WP_000916763.1 DNA polymerase III subunit theta -
NOF56_RS09705 2019599..2019973 + 375 WP_000204699.1 CopC domain-containing protein YobA -
NOF56_RS09710 2019977..2020849 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
NOF56_RS09715 2020862..2021203 + 342 WP_000976492.1 YebY family protein -
- 2021231..2021502 - 272 - - Antitoxin
- 2021361..2021464 + 104 - - Toxin
NOF56_RS09720 2021599..2022255 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
NOF56_RS09725 2022256..2022447 - 192 WP_001296140.1 YebW family protein -
NOF56_RS09730 2022552..2022788 - 237 WP_001295499.1 YebV family protein -
NOF56_RS09735 2022906..2024345 - 1440 WP_000057023.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1984198..2037340 53142


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T252389 NZ_CP101615:2021361-2021464 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT252389 NZ_CP101615:c2021502-2021231 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References