Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1966388..1966533 Replicon chromosome
Accession NZ_CP101546
Organism Klebsiella pneumoniae subsp. pneumoniae strain KP82

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1966424..1966526 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1966388..1966533 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NMY34_RS09745 (NMY34_09735) 1961518..1963578 + 2061 WP_004151449.1 oligopeptidase B -
NMY34_RS09750 (NMY34_09740) 1963582..1964241 - 660 WP_002911407.1 exodeoxyribonuclease X -
NMY34_RS09755 (NMY34_09745) 1964320..1964550 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NMY34_RS09760 (NMY34_09750) 1964663..1965037 + 375 WP_004151448.1 CopC domain-containing protein YobA -
NMY34_RS09765 (NMY34_09755) 1965041..1965910 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
NMY34_RS09770 (NMY34_09760) 1965927..1966265 + 339 WP_002911404.1 YebY family protein -
- 1966388..1966533 - 146 - - Antitoxin
- 1966424..1966526 + 103 - - Toxin
NMY34_RS09775 (NMY34_09765) 1966902..1967045 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
NMY34_RS09780 (NMY34_09770) 1967150..1968118 - 969 WP_073971755.1 VirK/YbjX family protein -
NMY34_RS09785 (NMY34_09775) 1968275..1968928 + 654 WP_032441330.1 protein-serine/threonine phosphatase -
NMY34_RS09790 (NMY34_09780) 1968925..1969116 - 192 WP_002911395.1 YebW family protein -
NMY34_RS09795 (NMY34_09785) 1969214..1969453 - 240 WP_002911393.1 YebV family protein -
NMY34_RS09800 (NMY34_09790) 1969569..1971002 - 1434 WP_220231913.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T252264 NZ_CP101546:1966424-1966526 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT252264 NZ_CP101546:c1966533-1966388 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References