Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 205853..206523 Replicon plasmid pB
Accession NZ_CP101519
Organism Ensifer adhaerens strain NER9

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag MYG64_RS28920 Protein ID WP_127890236.1
Coordinates 206104..206523 (+) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag MYG64_RS28915 Protein ID WP_060529947.1
Coordinates 205853..206107 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MYG64_RS28890 (MYG64_28780) 200903..201844 + 942 WP_112975005.1 glyoxylate/hydroxypyruvate reductase A -
MYG64_RS28895 (MYG64_28785) 201920..203530 + 1611 WP_060529950.1 peptide ABC transporter substrate-binding protein -
MYG64_RS28900 (MYG64_28790) 203593..204546 + 954 WP_060529949.1 ABC transporter permease -
MYG64_RS28905 (MYG64_28795) 204539..205420 + 882 WP_255382003.1 ABC transporter permease -
MYG64_RS28910 (MYG64_28800) 205552..205801 + 250 Protein_187 type II toxin-antitoxin system RelE/ParE family toxin -
MYG64_RS28915 (MYG64_28805) 205853..206107 + 255 WP_060529947.1 hypothetical protein Antitoxin
MYG64_RS28920 (MYG64_28810) 206104..206523 + 420 WP_127890236.1 type II toxin-antitoxin system VapC family toxin Toxin
MYG64_RS28925 (MYG64_28815) 206722..207057 + 336 WP_113188403.1 hypothetical protein -
MYG64_RS28930 (MYG64_28820) 207362..208189 + 828 WP_090302201.1 transporter substrate-binding domain-containing protein -
MYG64_RS28935 (MYG64_28825) 208249..209529 + 1281 WP_255382010.1 FAD-binding oxidoreductase -
MYG64_RS28940 (MYG64_28830) 209559..210530 + 972 WP_060644205.1 amino acid ABC transporter permease -
MYG64_RS28945 (MYG64_28835) 210538..211410 + 873 WP_255382013.1 DMT family transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - - 1..1586769 1586769


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-123)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 14783.84 Da        Isoelectric Point: 4.6556

>T252193 WP_127890236.1 NZ_CP101519:206104-206523 [Ensifer adhaerens]
MIVLDTNVVSEAMKPAPDLAVRNWLNDQVAETLYLSSVTLAELLFGIAALPEGRRKKALADTLDGLLELFDDRVLSFDTA
AARHYADLAATARAGGKGFPTPDGYIAAIAASKGFTIATRDTSPFEAAGVPVVNPWNHL

Download         Length: 420 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9581.88 Da        Isoelectric Point: 5.7425

>AT252193 WP_060529947.1 NZ_CP101519:205853-206107 [Ensifer adhaerens]
MAILTVRNVPDEVHRALRVRAANHGRSTEAEVREILERAVKPEQRIRIGDALAELSGRIGLTNDDFEVFDQMRDKAPAEP
MRFE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References