Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 160077..160717 Replicon plasmid pB
Accession NZ_CP101519
Organism Ensifer adhaerens strain NER9

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag MYG64_RS28710 Protein ID WP_060520810.1
Coordinates 160077..160463 (-) Length 129 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A1G9VC88
Locus tag MYG64_RS28715 Protein ID WP_034798574.1
Coordinates 160463..160717 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MYG64_RS28690 (MYG64_28580) 155661..156581 - 921 WP_060520814.1 ABC transporter permease subunit -
MYG64_RS28695 (MYG64_28585) 156598..157713 - 1116 WP_255381982.1 sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC -
MYG64_RS28700 (MYG64_28590) 157742..158524 - 783 WP_192439283.1 GntR family transcriptional regulator -
MYG64_RS28705 (MYG64_28595) 159726..159875 - 150 Protein_146 integrase -
MYG64_RS28710 (MYG64_28600) 160077..160463 - 387 WP_060520810.1 type II toxin-antitoxin system VapC family toxin Toxin
MYG64_RS28715 (MYG64_28605) 160463..160717 - 255 WP_034798574.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
MYG64_RS28720 (MYG64_28610) 161437..161682 - 246 WP_060521307.1 hypothetical protein -
MYG64_RS28725 (MYG64_28615) 162459..163943 + 1485 WP_082936527.1 IS21 family transposase -
MYG64_RS28730 (MYG64_28620) 163940..164821 + 882 WP_255381985.1 IS21-like element helper ATPase IstB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - - 1..1586769 1586769


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-124)

Antitoxin

Antitoxin VapB-like

(1-83)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 13986.77 Da        Isoelectric Point: 4.5034

>T252192 WP_060520810.1 NZ_CP101519:c160463-160077 [Ensifer adhaerens]
MVIDTSVLAAIAFNEPEAAAFRERIADDPVRLISAATVLEAAMVIETRLGEAAGADLDLWLYKAEVEIVPVTAEHSDRAR
RAWRRYGKGRHPASLNYGDCFSYALAALSGEPLLYKSNDFSQTDIEAA

Download         Length: 387 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9501.70 Da        Isoelectric Point: 5.1864

>AT252192 WP_034798574.1 NZ_CP101519:c160717-160463 [Ensifer adhaerens]
MALSIKDHDTEQLARTLAERTGESITLATKRALEERLRRLGSDLRKAALLEDLEAIQRRWNARPVLDSRTADEILGYDEN
GLPS

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A1G9VC88

References