Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 1523391..1524051 Replicon chromosome
Accession NZ_CP101375
Organism Salmonella enterica strain SC2016090

Toxin (Protein)


Gene name cptA Uniprot ID Q57K70
Locus tag NMU33_RS07515 Protein ID WP_000244756.1
Coordinates 1523638..1524051 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID S5MU13
Locus tag NMU33_RS07510 Protein ID WP_000351186.1
Coordinates 1523391..1523657 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NMU33_RS07490 (1519319) 1519319..1520752 - 1434 WP_001230141.1 6-phospho-beta-glucosidase BglA -
NMU33_RS07495 (1520911) 1520911..1521222 + 312 WP_001182976.1 N(4)-acetylcytidine aminohydrolase -
NMU33_RS07500 (1521386) 1521386..1522045 + 660 WP_000250289.1 hemolysin III family protein -
NMU33_RS07505 (1522161) 1522161..1523141 - 981 WP_000874172.1 tRNA-modifying protein YgfZ -
NMU33_RS07510 (1523391) 1523391..1523657 + 267 WP_000351186.1 FAD assembly factor SdhE Antitoxin
NMU33_RS07515 (1523638) 1523638..1524051 + 414 WP_000244756.1 protein YgfX Toxin
NMU33_RS07520 (1524104) 1524104..1524625 - 522 WP_001055885.1 flavodoxin FldB -
NMU33_RS07525 (1524738) 1524738..1525634 + 897 WP_000434302.1 site-specific tyrosine recombinase XerD -
NMU33_RS07530 (1525658) 1525658..1526371 + 714 WP_000745625.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
NMU33_RS07535 (1526377) 1526377..1528110 + 1734 WP_000813394.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16183.15 Da        Isoelectric Point: 10.7537

>T251993 WP_000244756.1 NZ_CP101375:1523638-1524051 [Salmonella enterica]
VVLWQSDLRVSWRAQWISLLIHGLVAAVILLMPWPLSYTPLWMILLSLVVFDCVRSQRRINTCQGEIKLLMDGRLRWQGQ
DWTLLRPPWLLKSGMVLRLRAESGRHQHLWLAADSMEEAEWRELRRILLQQPISGQH

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10550.05 Da        Isoelectric Point: 6.0783

>AT251993 WP_000351186.1 NZ_CP101375:1523391-1523657 [Salmonella enterica]
MDIHNKARIHWACRRGMRELDISIMPFFEHEYDSLSDEEKRIFVRLLQSDDPDLFNWLMNHGKPADAELEQMVRLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3Z1E9V5

Antitoxin

Source ID Structure
AlphaFold DB A0A5I0YWH4

References