Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 86721..87433 Replicon chromosome
Accession NZ_CP101369
Organism Salmonella enterica strain SC2014238

Toxin (Protein)


Gene name yeeV Uniprot ID A0A8F0CU93
Locus tag NMU30_RS00725 Protein ID WP_023216836.1
Coordinates 86721..87089 (-) Length 123 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID A0A8E7K1A9
Locus tag NMU30_RS00730 Protein ID WP_023216835.1
Coordinates 87104..87433 (-) Length 110 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NMU30_RS00695 (82254) 82254..82385 - 132 WP_023216841.1 hypothetical protein -
NMU30_RS00700 (82766) 82766..83105 + 340 Protein_78 transposase -
NMU30_RS00705 (83512) 83512..84345 - 834 WP_023216839.1 DUF4942 domain-containing protein -
NMU30_RS00710 (84499) 84499..85221 - 723 WP_077957236.1 retron system putative HNH endonuclease -
NMU30_RS00715 (85218) 85218..85439 - 222 WP_133297822.1 hypothetical protein -
NMU30_RS00720 (85424) 85424..86627 - 1204 Protein_82 AAA family ATPase -
NMU30_RS00725 (86721) 86721..87089 - 369 WP_023216836.1 TA system toxin CbtA family protein Toxin
NMU30_RS00730 (87104) 87104..87433 - 330 WP_023216835.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
NMU30_RS00735 (87496) 87496..87996 - 501 WP_023216834.1 DNA repair protein RadC -
NMU30_RS00740 (88009) 88009..88830 - 822 Protein_86 DUF945 domain-containing protein -
NMU30_RS00745 (88915) 88915..89829 - 915 WP_023216831.1 hypothetical protein -
NMU30_RS00750 (89894) 89894..90097 - 204 WP_023216830.1 hypothetical protein -
NMU30_RS00755 (90114) 90114..90260 - 147 WP_023892166.1 hypothetical protein -
NMU30_RS00760 (90333) 90333..91046 - 714 WP_023216829.1 WYL domain-containing protein -
NMU30_RS00765 (91428) 91428..91796 + 369 WP_165850589.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 82254..100181 17927


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(11-109)

Antitoxin

Antitoxin CbeA

(10-108)


Sequences

Toxin        


Download         Length: 123 a.a.        Molecular weight: 13735.76 Da        Isoelectric Point: 9.0721

>T251921 WP_023216836.1 NZ_CP101369:c87089-86721 [Salmonella enterica]
MQNVLSLPSPAAASSRLSPVEAWQKLLSYLLQRHYGLELNDTPFCDDIVIQEHINAGVALADAVNFLVEKYGLVRIDRKG
FSWQEQSPYLRAVDILRARKATGLLTRCKKHNGNQPDGRFTL

Download         Length: 369 bp

Antitoxin


Download         Length: 110 a.a.        Molecular weight: 12104.58 Da        Isoelectric Point: 6.4711

>AT251921 WP_023216835.1 NZ_CP101369:c87433-87104 [Salmonella enterica]
MPQNQPSAPVWGLRSDITPSFGARLVQEGCRLHFLPDRASLRGDFTAEQLHSLDITFPQFVKQLESALKSGALDPHQSRR
YSTILNGLTCEADTNGSHGYVYLTIYPAE

Download         Length: 330 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References