Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 4068495..4069057 Replicon chromosome
Accession NZ_CP101180
Organism Paenarthrobacter ureafaciens strain SD-2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NL395_RS19175 Protein ID WP_021472908.1
Coordinates 4068767..4069057 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A7M2BYL4
Locus tag NL395_RS19170 Protein ID WP_021472907.1
Coordinates 4068495..4068770 (+) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NL395_RS19150 (NL395_19100) 4064718..4065755 - 1038 WP_031216691.1 zinc-dependent alcohol dehydrogenase family protein -
NL395_RS19155 (NL395_19105) 4065885..4066697 - 813 WP_021472904.1 hypothetical protein -
NL395_RS19160 (NL395_19110) 4066744..4067385 - 642 WP_021472905.1 LysE family translocator -
NL395_RS19165 (NL395_19115) 4067584..4068462 + 879 WP_043427191.1 prephenate dehydratase -
NL395_RS19170 (NL395_19120) 4068495..4068770 + 276 WP_021472907.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
NL395_RS19175 (NL395_19125) 4068767..4069057 + 291 WP_021472908.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NL395_RS19180 (NL395_19130) 4069069..4070046 - 978 WP_021472909.1 thioredoxin-disulfide reductase -
NL395_RS19185 (NL395_19135) 4070110..4072281 - 2172 WP_069696782.1 MMPL family transporter -
NL395_RS19190 (NL395_19140) 4072444..4073079 + 636 WP_259362707.1 MarR family transcriptional regulator -
NL395_RS19195 (NL395_19145) 4073160..4073975 + 816 WP_021474094.1 class I SAM-dependent methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(14-93)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-71)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10888.46 Da        Isoelectric Point: 10.0347

>T251468 WP_021472908.1 NZ_CP101180:4068767-4069057 [Paenarthrobacter ureafaciens]
VSNSSLEGEPWNIQVTSPALKTFHRLPEKAASAIVEFITGALAGNPHRLSKPLTNELLGMRTARRGDYRVLFTLDIEDHV
LYVHRIQHRADVYKPR

Download         Length: 291 bp

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10112.30 Da        Isoelectric Point: 4.6847

>AT251468 WP_021472907.1 NZ_CP101180:4068495-4068770 [Paenarthrobacter ureafaciens]
MKTVPLSEAKDKLSALVEEADTTHEIIQITRHGHPSAVLMSADDLESLQETIHWLSQPGLREDLAQARRDIAEGNTVSGD
DLRREFGLPPR

Download         Length: 276 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7M2BYL4

References