Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 4112211..4112727 Replicon chromosome
Accession NZ_CP100678
Organism Salmonella enterica subsp. enterica serovar Anatum strain R17.0809

Toxin (Protein)


Gene name relE Uniprot ID A0A5U7R3Q6
Locus tag NL708_RS19925 Protein ID WP_023243277.1
Coordinates 4112211..4112495 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID V7ISI8
Locus tag NL708_RS19930 Protein ID WP_000212724.1
Coordinates 4112485..4112727 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NL708_RS19910 (4107327) 4107327..4108979 + 1653 WP_023243275.1 alpha,alpha-phosphotrehalase -
NL708_RS19915 (4109388) 4109388..4111526 + 2139 WP_000187821.1 anaerobic ribonucleoside-triphosphate reductase -
NL708_RS19920 (4111743) 4111743..4112207 + 465 WP_023243276.1 anaerobic ribonucleoside-triphosphate reductase-activating protein -
NL708_RS19925 (4112211) 4112211..4112495 - 285 WP_023243277.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NL708_RS19930 (4112485) 4112485..4112727 - 243 WP_000212724.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
NL708_RS19935 (4112805) 4112805..4114718 - 1914 WP_001212131.1 BglG family transcription antiterminator -
NL708_RS19940 (4114735) 4114735..4115475 - 741 WP_023243278.1 KDGP aldolase family protein -
NL708_RS19945 (4115472) 4115472..4116590 - 1119 WP_023243279.1 DgaE family pyridoxal phosphate-dependent ammonia lyase -
NL708_RS19950 (4116574) 4116574..4117707 - 1134 WP_023243280.1 amidohydrolase/deacetylase family metallohydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-82)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-80)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10801.62 Da        Isoelectric Point: 9.6730

>T250979 WP_023243277.1 NZ_CP100678:c4112495-4112211 [Salmonella enterica subsp. enterica serovar Anatum]
MTYELEFDPRALKEWHKLGDTVKAQLKKKLADVLLNPRIDSACLNGLPDCYKIKLKSSGYRLVYQVRDDVVIVFVVAVGK
REHSAVYHDANKRL

Download         Length: 285 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8961.34 Da        Isoelectric Point: 5.0651

>AT250979 WP_000212724.1 NZ_CP100678:c4112727-4112485 [Salmonella enterica subsp. enterica serovar Anatum]
MATLNVRLDDKLKNEAYAVLEKLNITPTEAVRLLFQYVAETGRMPVKTVTLSDSEDALIQTVRERLSSPQKGIKVSLDDL

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A5U7R3Q6

Antitoxin

Source ID Structure
AlphaFold DB A0A5H5JRI5

References