Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 4787470..4788004 Replicon chromosome
Accession NZ_CP100442
Organism Flavobacterium plurextorum strain RSG-18

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag NLG42_RS20775 Protein ID WP_257682215.1
Coordinates 4787470..4787763 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag NLG42_RS20780 Protein ID WP_089056144.1
Coordinates 4787756..4788004 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NLG42_RS20745 (NLG42_20720) 4782835..4783524 + 690 WP_089056139.1 response regulator transcription factor -
NLG42_RS20750 (NLG42_20725) 4783557..4784099 - 543 WP_089056140.1 hypothetical protein -
NLG42_RS20755 (NLG42_20730) 4784190..4785107 - 918 WP_257682214.1 2-dehydropantoate 2-reductase -
NLG42_RS20760 (NLG42_20735) 4785223..4786473 - 1251 WP_099718953.1 cation:dicarboxylase symporter family transporter -
NLG42_RS20770 (NLG42_20745) 4786951..4787244 + 294 WP_089056142.1 hypothetical protein -
NLG42_RS20775 (NLG42_20750) 4787470..4787763 - 294 WP_257682215.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NLG42_RS20780 (NLG42_20755) 4787756..4788004 - 249 WP_089056144.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
NLG42_RS20785 (NLG42_20760) 4788104..4788553 - 450 WP_257682216.1 nuclear transport factor 2 family protein -
NLG42_RS20790 (NLG42_20765) 4788611..4789405 - 795 WP_099718958.1 peptidase -
NLG42_RS20795 (NLG42_20770) 4789514..4790170 + 657 WP_123922143.1 hypothetical protein -
NLG42_RS20800 (NLG42_20775) 4790231..4791316 + 1086 WP_089056148.1 DNA polymerase III subunit gamma/tau -
NLG42_RS20805 (NLG42_20780) 4791390..4791542 - 153 WP_257682217.1 hypothetical protein -
NLG42_RS20810 (NLG42_20785) 4791526..4791969 + 444 WP_257682218.1 DNA polymerase III subunit gamma/tau -
NLG42_RS20815 (NLG42_20790) 4792047..4792625 - 579 WP_099718961.1 NAD(P)H-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-92)

Antitoxin

Antitoxin ParD

(1-78)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11443.97 Da        Isoelectric Point: 4.8258

>T250563 WP_257682215.1 NZ_CP100442:c4787763-4787470 [Flavobacterium plurextorum]
MAKYHFTNKAVEDLADIWNYTFDEWSENQADKYYLLLLDSCQELAENPNLGKKYDTVAESLFGFKSNLHILFYQIISNTE
IEVVRILHGRMDLKSKF

Download         Length: 294 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9251.41 Da        Isoelectric Point: 8.7454

>AT250563 WP_089056144.1 NZ_CP100442:c4788004-4787756 [Flavobacterium plurextorum]
MGRNTSISLGNHFENFIENSLSEGRFKNASEVVRAGLRLLEEEENKLLILKKAVQEGLESGRAENFDSKKHLESLKANRK
HG

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References