Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2172665..2172933 Replicon chromosome
Accession NZ_CP099721
Organism Escherichia coli strain EC21GDE043

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2172793..2172895 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2172665..2172933 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NH569_RS10480 2169219..2169881 - 663 WP_000944256.1 exodeoxyribonuclease X -
NH569_RS10485 2169904..2170560 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein YobB -
NH569_RS10490 2170662..2170892 - 231 WP_000916763.1 DNA polymerase III subunit theta -
NH569_RS10495 2171031..2171405 + 375 WP_000168747.1 CopC domain-containing protein YobA -
NH569_RS10500 2171409..2172281 + 873 WP_000879320.1 copper homeostasis membrane protein CopD -
NH569_RS10505 2172294..2172635 + 342 WP_000984819.1 YebY family protein -
- 2172665..2172933 - 269 - - Antitoxin
- 2172793..2172895 + 103 - - Toxin
NH569_RS10510 2173030..2173686 + 657 WP_000812741.1 protein-serine/threonine phosphatase -
NH569_RS10515 2173687..2173878 - 192 WP_001296140.1 YebW family protein -
NH569_RS10520 2173983..2174219 - 237 WP_001295499.1 YebV family protein -
NH569_RS10525 2174337..2175776 - 1440 WP_001350670.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T249321 NZ_CP099721:2172793-2172895 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT249321 NZ_CP099721:c2172933-2172665 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References