Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 3560363..3561063 Replicon chromosome
Accession NZ_CP099625
Organism Paraburkholderia fungorum strain OTU2BAGNBA1

Toxin (Protein)


Gene name mqsR Uniprot ID A0A2T1AWY4
Locus tag NFE55_RS38630 Protein ID WP_030100731.1
Coordinates 3560363..3560659 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag NFE55_RS38635 Protein ID WP_028197207.1
Coordinates 3560662..3561063 (+) Length 134 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NFE55_RS38610 (NFE55_38615) 3555690..3555959 + 270 WP_028197212.1 DUF4148 domain-containing protein -
NFE55_RS38615 (NFE55_38620) 3556067..3557158 + 1092 WP_252890149.1 catalase family peroxidase -
NFE55_RS38620 (NFE55_38625) 3557155..3557694 + 540 WP_046570668.1 cytochrome b -
NFE55_RS38625 (NFE55_38630) 3557691..3560195 - 2505 WP_046570655.1 FAD-dependent oxidoreductase -
NFE55_RS38630 (NFE55_38635) 3560363..3560659 + 297 WP_030100731.1 type II toxin-antitoxin system MqsR family toxin Toxin
NFE55_RS38635 (NFE55_38640) 3560662..3561063 + 402 WP_028197207.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
NFE55_RS38640 (NFE55_38645) 3561169..3561948 + 780 WP_028197206.1 DeoR/GlpR family DNA-binding transcription regulator -
NFE55_RS38645 (NFE55_38650) 3562138..3565620 + 3483 WP_252890150.1 DEAD/DEAH box helicase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(5-97)

Antitoxin

(3-48)


Sequences


Toxin        


Download         Length: 99 a.a.        Molecular weight: 10739.53 Da        Isoelectric Point: 7.8545

>T249273 WP_030100731.1 NZ_CP099625:3560363-3560659 [Paraburkholderia fungorum]
MEKSTPHCKLAEVQSLARAGNIRITKSAVIGAAALGLGPAAIIETLLSLERGNFRKSMTTYADHRVWQDVYCAVTEAGMV
YLKLTVIDDVLVVSFKEW

Download         Length: 297 bp


Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14738.86 Da        Isoelectric Point: 5.0016

>AT249273 WP_028197207.1 NZ_CP099625:3560662-3561063 [Paraburkholderia fungorum]
MKCPNCGAAELVRDTRNMRYVYKGETAVFEAVTGDYCPACDEAVLDIDEATRTGQMMLAFNKEVNASQVDPAFIAAVRKK
LDLDQREAAEIFGGGVNAFSRYENGKTRPPLALIKLLKVLDRHPELLEEVRAS

Download         Length: 402 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A2T1AWY4


Antitoxin

Source ID Structure

References