Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 1569520..1570199 Replicon chromosome
Accession NZ_CP099542
Organism Pantoea ananatis strain JT8-6

Toxin (Protein)


Gene name yeeV Uniprot ID -
Locus tag NG830_RS07495 Protein ID WP_063933824.1
Coordinates 1569879..1570199 (+) Length 107 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID -
Locus tag NG830_RS07490 Protein ID WP_263775528.1
Coordinates 1569520..1569843 (+) Length 108 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NG830_RS07460 (NG830_07455) 1564535..1565320 + 786 WP_263775525.1 hypothetical protein -
NG830_RS07465 (NG830_07460) 1565539..1565757 - 219 WP_105091710.1 AlpA family phage regulatory protein -
NG830_RS07470 (NG830_07465) 1565849..1566496 - 648 WP_263775526.1 inovirus Gp2 family protein -
NG830_RS07475 (NG830_07470) 1567040..1567996 + 957 WP_263775527.1 hypothetical protein -
NG830_RS07480 (NG830_07475) 1568145..1568966 + 822 WP_058688734.1 DUF932 domain-containing protein -
NG830_RS07485 (NG830_07480) 1569037..1569507 + 471 WP_058688735.1 DNA repair protein RadC -
NG830_RS07490 (NG830_07485) 1569520..1569843 + 324 WP_263775528.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
NG830_RS07495 (NG830_07490) 1569879..1570199 + 321 WP_063933824.1 TA system toxin CbtA family protein Toxin
NG830_RS07500 (NG830_07495) 1570313..1571143 + 831 WP_263775529.1 DUF4942 domain-containing protein -
NG830_RS07505 (NG830_07500) 1571220..1572227 + 1008 WP_103270114.1 restriction endonuclease -
NG830_RS07510 (NG830_07505) 1572573..1573190 + 618 Protein_1453 integrase arm-type DNA-binding domain-containing protein -
NG830_RS07515 (NG830_07510) 1573385..1573660 + 276 Protein_1454 winged helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1555041..1573660 18619


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(5-105)

Antitoxin

Antitoxin CbeA

(7-106)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12007.60 Da        Isoelectric Point: 6.1195

>T249098 WP_063933824.1 NZ_CP099542:1569879-1570199 [Pantoea ananatis]
MHISTVPATVPVSSRLSPVQVWKQLLTYLLDHHYGLTLNDTPFHDDAAIEEHIDAGITLADAVNFLVERHELVRIDHKGF
TWYEQTSFLTATDILRARRATGLINT

Download         Length: 321 bp

Antitoxin


Download         Length: 108 a.a.        Molecular weight: 11975.70 Da        Isoelectric Point: 6.8578

>AT249098 WP_263775528.1 NZ_CP099542:1569520-1569843 [Pantoea ananatis]
MSITPPHEWGLQSDITPRFGARLVQEGNRLYYLADRAGLTGSFSPIHLQKLDLAFPLFVEQLENMLRAGELNSHKQHQVT
IQLASLTCIADTRGSCGYVYISIYPTP

Download         Length: 324 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References