Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vagCD/VapC-VagC
Location 85837..86489 Replicon chromosome
Accession NZ_CP099542
Organism Pantoea ananatis strain JT8-6

Toxin (Protein)


Gene name vagD Uniprot ID -
Locus tag NG830_RS00425 Protein ID WP_033778077.1
Coordinates 85837..86235 (-) Length 133 a.a.

Antitoxin (Protein)


Gene name vagC Uniprot ID -
Locus tag NG830_RS00430 Protein ID WP_028724117.1
Coordinates 86259..86489 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NG830_RS00405 (NG830_00400) 82724..83395 - 672 WP_221611350.1 fimbria/pilus periplasmic chaperone -
NG830_RS00410 (NG830_00405) 83458..84015 - 558 WP_252294282.1 fimbrial protein -
NG830_RS00415 (NG830_00410) 84424..84705 + 282 WP_028724120.1 LuxR C-terminal-related transcriptional regulator -
NG830_RS00420 (NG830_00415) 84735..85610 + 876 WP_252294280.1 N-acetylmuramoyl-L-alanine amidase -
NG830_RS00425 (NG830_00420) 85837..86235 - 399 WP_033778077.1 type II toxin-antitoxin system VapC family toxin Toxin
NG830_RS00430 (NG830_00425) 86259..86489 - 231 WP_028724117.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
NG830_RS00435 (NG830_00430) 87077..88235 + 1159 Protein_86 IS30 family transposase -
NG830_RS00440 (NG830_00435) 88719..89273 - 555 WP_263775424.1 hypothetical protein -
NG830_RS00445 (NG830_00440) 89327..89491 - 165 Protein_88 conjugal transfer protein TraF -
NG830_RS00450 (NG830_00445) 89489..89722 + 234 Protein_89 TIGR03752 family integrating conjugative element protein -
NG830_RS00455 (NG830_00450) 89722..89994 + 273 WP_263775425.1 hypothetical protein -
NG830_RS00460 (NG830_00455) 89984..90397 + 414 WP_210456553.1 TIGR03751 family conjugal transfer lipoprotein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 47091..112090 64999


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-124)

Antitoxin

SpoVT-AbrB domain

(7-52)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 14290.62 Da        Isoelectric Point: 7.2161

>T249097 WP_033778077.1 NZ_CP099542:c86235-85837 [Pantoea ananatis]
MLDTCICSFIMREQPEAVLKRLEQAVLRGHRIVVSAITYAEMRFGASGPKASPRHVQLVDAFCARLDAVLPWDRAAVDAT
TEIKVSLRLAGTPIGPNDTAIAGHAITVGAILVTNNVREFARVPGLALEDWV

Download         Length: 399 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8702.83 Da        Isoelectric Point: 4.6158

>AT249097 WP_028724117.1 NZ_CP099542:c86489-86259 [Pantoea ananatis]
MRTVSIFKNGNNRAIRLPRDLDFDGVSELEIVREGDSIILRPVRPTWGSFLELEKADPHFMAERGDVVSDEGRFDL

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References