Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/HicA-HicA
Location 4476846..4477258 Replicon chromosome
Accession NZ_CP099531
Organism Xanthomonas sacchari strain HR3-46

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag NG825_RS19160 Protein ID WP_284467881.1
Coordinates 4477064..4477258 (-) Length 65 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag NG825_RS19155 Protein ID WP_284467880.1
Coordinates 4476846..4477058 (-) Length 71 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NG825_RS19140 (NG825_19110) 4472672..4473358 - 687 WP_284467877.1 hypothetical protein -
NG825_RS19145 (NG825_19115) 4473365..4475380 - 2016 WP_284467878.1 ATP-binding protein -
NG825_RS19150 (NG825_19120) 4475433..4476743 - 1311 WP_284467879.1 Eco57I restriction-modification methylase domain-containing protein -
NG825_RS19155 (NG825_19125) 4476846..4477058 - 213 WP_284467880.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
NG825_RS19160 (NG825_19130) 4477064..4477258 - 195 WP_284467881.1 type II toxin-antitoxin system HicA family toxin Toxin
NG825_RS19165 (NG825_19135) 4477375..4480065 - 2691 WP_150409817.1 pyruvate dehydrogenase (acetyl-transferring), homodimeric type -
NG825_RS19170 (NG825_19140) 4480282..4482258 + 1977 WP_284468869.1 SpoIIE family protein phosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4445301..4477258 31957


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(6-61)

Antitoxin

HicB-like antitoxin of toxin-antitoxin system

(3-62)


Sequences

Toxin        


Download         Length: 65 a.a.        Molecular weight: 7033.09 Da        Isoelectric Point: 11.0837

>T249081 WP_284467881.1 NZ_CP099531:c4477258-4477064 [Xanthomonas sacchari]
MPPKIRDVLQQLKDAGWQQVGQTGSHRQFKHPVYPGRVTVAGKPSDDVAPGTLNSILKQASLKR

Download         Length: 195 bp

Antitoxin


Download         Length: 71 a.a.        Molecular weight: 7404.37 Da        Isoelectric Point: 4.0830

>AT249081 WP_284467880.1 NZ_CP099531:c4477058-4476846 [Xanthomonas sacchari]
MRYAVVIEQAGNNYSAYVPDLPGCVATGATTAEVEGLIREAIKLHLAGMREDGEVIPPPSSQVEYVDVAA

Download         Length: 213 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References